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Mechanistically informed circulating biomarkers are associated with acquired epilepsy after neonatal brain injury.

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Title: Mechanistically informed circulating biomarkers are associated with acquired epilepsy after neonatal brain injury.
Authors: Numis AL; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA. Adam.numis@ucsf.edu.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA. Adam.numis@ucsf.edu., Shellhaas RA; Department of Neurology, Washington University in St. Louis, St. Louis, MO, 63110, USA., Soul JS; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Gardner MA; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA., Wusthoff CJ; Department of Neurology, University of California Davis, Davis, CA, 95616, USA., Benedetti GM; Department of Pediatrics, Division of Pediatric Neurology, University of Michigan, Ann Arbor, MI, 48108, USA., Di Germanio C; Vitalant Research Institute, Core Immunology Laboratory, San Francisco, CA, 94105, USA.; Department of Medicine, University of California, San Francisco, CA, 94143, USA., Bammler TK; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 98195, USA.; Department of Biostatistics, University of Washington, Seattle, WA, 98195, USA., Erle DJ; Department of Medicine, University of California, San Francisco, CA, 94143, USA., Eckalbar WL; Department of Medicine, University of California, San Francisco, CA, 94143, USA., McCulloch CE; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, 94143, USA., Heagerty PJ; Department of Biostatistics, University of Washington, Seattle, WA, 98195, USA., Wood TR; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA., Wu YW; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA., Juul SE; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA., Lowenstein DH; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA., Glass HC; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, 94143, USA.
Corporate Authors: Neonatal Seizure Registry Study Group, HEAL Consortium
Source: Journal of neuroinflammation [J Neuroinflammation] 2026 May 09; Vol. 23 (1). Date of Electronic Publication: 2026 May 09.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Mechanistically informed circulating biomarkers are associated with acquired epilepsy after neonatal brain injury.
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  Data: <searchLink fieldCode="AU" term="%22Numis+AL%22">Numis AL</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA. Adam.numis@ucsf.edu.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA. Adam.numis@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Shellhaas+RA%22">Shellhaas RA</searchLink>; Department of Neurology, Washington University in St. Louis, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Soul+JS%22">Soul JS</searchLink>; Department of Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Gardner+MA%22">Gardner MA</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Wusthoff+CJ%22">Wusthoff CJ</searchLink>; Department of Neurology, University of California Davis, Davis, CA, 95616, USA.<br /><searchLink fieldCode="AU" term="%22Benedetti+GM%22">Benedetti GM</searchLink>; Department of Pediatrics, Division of Pediatric Neurology, University of Michigan, Ann Arbor, MI, 48108, USA.<br /><searchLink fieldCode="AU" term="%22Di+Germanio+C%22">Di Germanio C</searchLink>; Vitalant Research Institute, Core Immunology Laboratory, San Francisco, CA, 94105, USA.; Department of Medicine, University of California, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Bammler+TK%22">Bammler TK</searchLink>; Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 98195, USA.; Department of Biostatistics, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Erle+DJ%22">Erle DJ</searchLink>; Department of Medicine, University of California, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Eckalbar+WL%22">Eckalbar WL</searchLink>; Department of Medicine, University of California, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22McCulloch+CE%22">McCulloch CE</searchLink>; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Heagerty+PJ%22">Heagerty PJ</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Wood+TR%22">Wood TR</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Wu+YW%22">Wu YW</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Juul+SE%22">Juul SE</searchLink>; Department of Pediatrics, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Lowenstein+DH%22">Lowenstein DH</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Glass+HC%22">Glass HC</searchLink>; Department of Neurology and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, 94143, USA.
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  Data: <searchLink fieldCode="CA" term="%22Neonatal+Seizure+Registry+Study+Group%22">Neonatal Seizure Registry Study Group</searchLink><br /><searchLink fieldCode="CA" term="%22HEAL+Consortium%22">HEAL Consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101222974%22">Journal of neuroinflammation</searchLink> [J Neuroinflammation] 2026 May 09; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 May 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101222974 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-2094 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217422094%22">17422094 </searchLink><i>NLM ISO Abbreviation: </i>J Neuroinflammation <i>Subsets: </i>MEDLINE
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