Tilorone suppresses TGF-β-driven fibroblast activation and restores BMP-Smad1/5/8 signaling: implications for laryngotracheal fibrosis.
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| Title: | Tilorone suppresses TGF-β-driven fibroblast activation and restores BMP-Smad1/5/8 signaling: implications for laryngotracheal fibrosis. |
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| Authors: | Toth E; Department of Biochemistry, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary.; Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary., Szabo K; Department of Biochemistry, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary., Vegh AG; Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, Hungary., Zvara A; Laboratory of Functional Genomics, HUN-REN Biological Research Centre, Szeged, Hungary., Puskas LG; Laboratory of Functional Genomics, HUN-REN Biological Research Centre, Szeged, Hungary., Bach A; Department of Oto-Rhino-Laryngology and Head-Neck Surgery, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary., Migh E; Synthetic and Systems Biology Unit, HUN-REN Biological Research Centre, Szeged, Hungary., Horvath P; Synthetic and Systems Biology Unit, HUN-REN Biological Research Centre, Szeged, Hungary.; Single-Cell Technologies Ltd, Szeged, Hungary.; Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland.; Institute of AI for Health, Helmholtz Zentrum München, Neuherberg, Germany., Tiszlavicz L; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary., Rovo L; Department of Oto-Rhino-Laryngology and Head-Neck Surgery, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary., Keller-Pinter A; Department of Biochemistry, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary. keller.aniko@med.u-szeged.hu.; Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary. keller.aniko@med.u-szeged.hu.; Department of Internal Medicine, Albert Szent-Gyorgyi Medical School, University of Szeged, Szeged, Hungary. keller.aniko@med.u-szeged.hu. |
| Source: | Journal of translational medicine [J Transl Med] 2026 May 09. Date of Electronic Publication: 2026 May 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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