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Brain-age defines a structural signature of outcomes after vagus nerve stimulation in children.

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Title: Brain-age defines a structural signature of outcomes after vagus nerve stimulation in children.
Authors: Latypov TH; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada., Suresh H; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Gouveia FV; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada., Mithani K; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Berger A; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada., Wong SM; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada., Coleman SC; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada., Weiss S; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada., Sham L; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada., Chau V; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada., Hadjinicolaou A; Division of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada., Major P; Division of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada., Weil AG; Division of Neurosurgery, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada., Tailor J; Department of Neurological Surgery, Indiana University School of Medicine, IN, United States of America., Abel TJ; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America., Remick M; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America., Akwayena E; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America., Schrader D; Department of Pediatrics, British Columbia Children's Hospital, Vancouver, BC, Canada., Bollo RJ; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, United States of America., Smyth MD; Department of Neurological Surgery, Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States of America., Aum D; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America., Lew S; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America., Wang S; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, FL, United States of America., Niazi T; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, FL, United States of America., Raskin JS; Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States of America., Widjaja E; Department of Medical Imaging, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States of America., Albert GW; Division of Neurosurgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR, United States of America., Weiner HL; Division of Pediatric Neurosurgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States of America., Gadgil N; Division of Pediatric Neurosurgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States of America., LoPresti MA; Department of Neurosurgery, University of Rochester Medical Center, New York, United States of America., Fallah A; Department of Neurosurgery, David Geffen School of Medicine at the University of California, Los Angeles, CA, United States of America., Kerr EN; Department of Psychology, Hospital for Sick Children, Toronto, ON, Canada., Jain P; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada., Christian E; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada., Donner E; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada., Rutka JT; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada., Ibrahim GM; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada. Electronic address: george.ibrahim@sickkids.ca.
Source: Brain stimulation [Brain Stimul] 2026 Jul-Aug; Vol. 19 (4), pp. 103117. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101465726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-4754 (Electronic) Linking ISSN: 18764754 NLM ISO Abbreviation: Brain Stimul Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: <searchLink fieldCode="AU" term="%22Latypov+TH%22">Latypov TH</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Suresh+H%22">Suresh H</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gouveia+FV%22">Gouveia FV</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Mithani+K%22">Mithani K</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Berger+A%22">Berger A</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Wong+SM%22">Wong SM</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Coleman+SC%22">Coleman SC</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Weiss+S%22">Weiss S</searchLink>; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Sham+L%22">Sham L</searchLink>; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Chau+V%22">Chau V</searchLink>; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hadjinicolaou+A%22">Hadjinicolaou A</searchLink>; Division of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Major+P%22">Major P</searchLink>; Division of Pediatrics, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Weil+AG%22">Weil AG</searchLink>; Division of Neurosurgery, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Tailor+J%22">Tailor J</searchLink>; Department of Neurological Surgery, Indiana University School of Medicine, IN, United States of America.<br /><searchLink fieldCode="AU" term="%22Abel+TJ%22">Abel TJ</searchLink>; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America.<br /><searchLink fieldCode="AU" term="%22Remick+M%22">Remick M</searchLink>; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America.<br /><searchLink fieldCode="AU" term="%22Akwayena+E%22">Akwayena E</searchLink>; Department of Neurological Surgery and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States of America.<br /><searchLink fieldCode="AU" term="%22Schrader+D%22">Schrader D</searchLink>; Department of Pediatrics, British Columbia Children's Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Bollo+RJ%22">Bollo RJ</searchLink>; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, United States of America.<br /><searchLink fieldCode="AU" term="%22Smyth+MD%22">Smyth MD</searchLink>; Department of Neurological Surgery, Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States of America.<br /><searchLink fieldCode="AU" term="%22Aum+D%22">Aum D</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Lew+S%22">Lew S</searchLink>; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States of America.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, FL, United States of America.<br /><searchLink fieldCode="AU" term="%22Niazi+T%22">Niazi T</searchLink>; Department of Neurosurgery, Nicklaus Children's Hospital, Miami, FL, United States of America.<br /><searchLink fieldCode="AU" term="%22Raskin+JS%22">Raskin JS</searchLink>; Division of Pediatric Neurosurgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States of America.<br /><searchLink fieldCode="AU" term="%22Widjaja+E%22">Widjaja E</searchLink>; Department of Medical Imaging, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States of America.<br /><searchLink fieldCode="AU" term="%22Albert+GW%22">Albert GW</searchLink>; Division of Neurosurgery, Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR, United States of America.<br /><searchLink fieldCode="AU" term="%22Weiner+HL%22">Weiner HL</searchLink>; Division of Pediatric Neurosurgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States of America.<br /><searchLink fieldCode="AU" term="%22Gadgil+N%22">Gadgil N</searchLink>; Division of Pediatric Neurosurgery, Department of Surgery, Texas Children's Hospital, Houston, TX, United States of America.<br /><searchLink fieldCode="AU" term="%22LoPresti+MA%22">LoPresti MA</searchLink>; Department of Neurosurgery, University of Rochester Medical Center, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Fallah+A%22">Fallah A</searchLink>; Department of Neurosurgery, David Geffen School of Medicine at the University of California, Los Angeles, CA, United States of America.<br /><searchLink fieldCode="AU" term="%22Kerr+EN%22">Kerr EN</searchLink>; Department of Psychology, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Jain+P%22">Jain P</searchLink>; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Christian+E%22">Christian E</searchLink>; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Donner+E%22">Donner E</searchLink>; Division of Neurology, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rutka+JT%22">Rutka JT</searchLink>; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Ibrahim+GM%22">Ibrahim GM</searchLink>; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada. Electronic address: george.ibrahim@sickkids.ca.
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  Data: <searchLink fieldCode="JN" term="%22101465726%22">Brain stimulation</searchLink> [Brain Stimul] 2026 Jul-Aug; Vol. 19 (4), pp. 103117. <i>Date of Electronic Publication: </i>2026 May 08.
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