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Comorbidity Alters the Genetic Relationship Between Anxiety Disorders and Major Depression.

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Title: Comorbidity Alters the Genetic Relationship Between Anxiety Disorders and Major Depression.
Authors: Tesfaye M; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health, State University of New York Downstate Health Sciences University, Brooklyn, New York; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Health Sciences University, Brooklyn, New York. Electronic address: m.t.woldeyohannes@medisin.uio.no., Shadrin A; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway., Parker N; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Jaholkowski P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Parekh P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California., Kutrolli G; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health, State University of New York Downstate Health Sciences University, Brooklyn, New York., Birkenæs V; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Regional Centre for Children and Youth Mental Health, Oslo, Norway., Bakken NR; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Ask H; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway; Department of Psychology, PROMENTA Research Center, University of Oslo, Oslo, Norway., Hindley G; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Psychiatry, Lovisenberg Diaconal Hospital, Oslo, Norway., Frei O; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Informatics, Center for Bioinformatics, University of Oslo, Oslo, Norway., Djurovic S; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Dale AM; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California; Department of Neurosciences, University of California San Diego, La Jolla, California., Smeland OB; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., O'Connell KS; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Andreassen OA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: o.a.andreassen@medisin.uio.no.
Source: Biological psychiatry [Biol Psychiatry] 2026 May 08. Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0213264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2402 (Electronic) Linking ISSN: 00063223 NLM ISO Abbreviation: Biol Psychiatry Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Tesfaye+M%22">Tesfaye M</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health, State University of New York Downstate Health Sciences University, Brooklyn, New York; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Health Sciences University, Brooklyn, New York. Electronic address: m.t.woldeyohannes@medisin.uio.no.<br /><searchLink fieldCode="AU" term="%22Shadrin+A%22">Shadrin A</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Parker+N%22">Parker N</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Jaholkowski+P%22">Jaholkowski P</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Parekh+P%22">Parekh P</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California.<br /><searchLink fieldCode="AU" term="%22Kutrolli+G%22">Kutrolli G</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health, State University of New York Downstate Health Sciences University, Brooklyn, New York.<br /><searchLink fieldCode="AU" term="%22Birkenæs+V%22">Birkenæs V</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Regional Centre for Children and Youth Mental Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Bakken+NR%22">Bakken NR</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Ask+H%22">Ask H</searchLink>; PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway; Department of Psychology, PROMENTA Research Center, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hindley+G%22">Hindley G</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Psychiatry, Lovisenberg Diaconal Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Frei+O%22">Frei O</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Informatics, Center for Bioinformatics, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Djurovic+S%22">Djurovic S</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dale+AM%22">Dale AM</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, California; Department of Neurosciences, University of California San Diego, La Jolla, California.<br /><searchLink fieldCode="AU" term="%22Smeland+OB%22">Smeland OB</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22O'Connell+KS%22">O'Connell KS</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: o.a.andreassen@medisin.uio.no.
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