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A Severity-Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA-Ataxia.

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Title: A Severity-Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA-Ataxia.
Authors: Robertson JW; Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada., Adanyeguh I; Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Arpin DJ; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, Florida, USA., Ashizawa T; Department of Neurology, Weill Cornell Medicine at Houston Methodist Research Institute, Houston, Texas, USA., Bender B; Department of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Tübingen, Germany., Cendes F; Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), School of Medical Sciences, University of Campinas, Campinas, Brazil., Chen X; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China., Coarelli G; Sorbonne Université, Paris Brain Institute (ICM), Pitié-Salpêtrière Hospital, AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France., Coutinho L; Post-Graduate Program of Internal Medicine, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil., Deistung A; Department for Radiation Medicine, University Clinic and Outpatient Clinic for Radiology, University Hospital Halle (Saale), University Medicine Halle, Halle (Saale), Germany., Dogan I; Department of Neurology, RWTH Aachen University, Aachen, Germany.; JARA-BRAIN Institute Molecular Neuroscience and Neuroimaging, Research Center Jülich GmbH, Jülich, Germany., Durr A; Sorbonne Université, Paris Brain Institute (ICM), Pitié-Salpêtrière Hospital, AP-HP, INSERM, CNRS, University Hospital Pitié-Salpêtrière, Paris, France., Faber J; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Parkinson's Disease, Sleep and Movement Disorders, Center of Neurology, University Hospital Bonn, Bonn, Germany.; Department of Neuroradiology, University Hospital Bonn, Bonn, Germany., Fernandez-Ruiz J; Neuropsychology Laboratory, Department of Physiology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico., Ferreira M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neuroradiology, University of Bonn, Bonn, Germany., França MC; Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), School of Medical Sciences, University of Campinas, Campinas, Brazil., Göricke SL; Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Essen University Hospital, University of Duisburg-Essen, Essen, Germany.; Institute of Diagnostic and Interventional Radiology and Neuroradiology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany., Han S; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Klockgether T; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Liu C; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China., Luo J; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China., Martinez ARM; Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), School of Medical Sciences, University of Campinas, Campinas, Brazil., Ono SE; Clínica DAPI-Diagnóstico Avançado Por Imagem, Curitiba, Brazil., Onyike CU; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, USA., Öz G; Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Paulson H; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA., Prince JL; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Reetz K; Department of Neurology, RWTH Aachen University, Aachen, Germany.; JARA-BRAIN Institute Molecular Neuroscience and Neuroimaging, Research Center Jülich GmbH, Jülich, Germany., Rezende TJR; Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), School of Medical Sciences, University of Campinas, Campinas, Brazil., Synofzik M; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Ghizoni Teive HA; Post-Graduate Program of Internal Medicine, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil.; Movement Disorders Unit, Neurology Service, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil., Thomopoulos SI; Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Marina del Rey, California, USA., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Marina del Rey, California, USA., Timmann D; Center for Translational Neuro- and Behavioral Sciences (C-TNBS), Essen University Hospital, University of Duisburg-Essen, Essen, Germany.; Department of Neurology, Essen University Hospital, University of Duisburg-Essen, Essen, Germany., Vaillancourt D; Department of Applied Physiology & Kinesiology, University of Florida, Gainesville, Florida, USA.; Department of Neurology, University of Florida, Gainesville, Florida, USA.; Norman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, Florida, USA., van de Warrenburg B; Department of Neurology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., van Gaalen J; Department of Neurology, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Neurology, Rijnstate Hospital, Arnhem, The Netherlands., Wang X; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China., Wegner P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neuroradiology, University of Bonn, Bonn, Germany., Ying SH; Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA., Harding IH; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; School of Translational Medicine, Monash University, Melbourne, Victoria, Australia., Hernandez-Castillo CR; Faculty of Computer Science, Dalhousie University, Halifax, Nova Scotia, Canada.
Corporate Authors: ESMI MR Study Group, EUROSCA MR Study Group
Source: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2026 May 10. Date of Electronic Publication: 2026 May 10.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: A Severity-Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA-Ataxia.
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Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Klockgether+T%22">Klockgether T</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Luo+J%22">Luo J</searchLink>; 7T Magnetic Resonance Imaging Translational Medical Center, Department of Radiology, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Martinez+ARM%22">Martinez ARM</searchLink>; Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, Brazil.; Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), School of Medical Sciences, University of Campinas, Campinas, Brazil.<br /><searchLink fieldCode="AU" term="%22Ono+SE%22">Ono SE</searchLink>; 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