Alzheimer's Disease Co-Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis.

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Title: Alzheimer's Disease Co-Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis.
Authors: Kasper E; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany., Lehto A; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany., Jürs A; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany., Nordmann N; Department of Neurology, Rostock University Medical Center, Rostock, Germany., Peters O; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin-Institute of Psychiatry and Psychotherapy, Berlin, Germany., Hellmann J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuropsychiatry and Laboratory of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Center for Mental Health (DZPG), Munich, Germany.; University of Edinburgh and UK DRI, Edinburgh, UK., Spruth EJ; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuropsychiatry and Laboratory of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Petzold GC; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Vascular Neurology, University Hospital Bonn, Bonn, Germany., Voigt I; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Weydt P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Bernsen S; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Dinter E; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Falkenburger B; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Günther R; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University, Magdeburg, Germany.; Institute of Cognitive Neuroscience, University College London, London, UK., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University, Magdeburg, Germany., Synofzik M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division of Translational Genomics of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany., Beichert L; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division of Translational Genomics of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany., Spottke A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany., Brosseron F; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Schmid MC; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany., Halle A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neuropathology, University of Bonn, Bonn, Germany., Herms J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Department of Neurology, University Hospital of Munich, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Prudlo J; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany., Neumann M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Neuropathology, Tübingen University Hospital, Tübingen, Germany., Hermann A; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany.
Source: Annals of neurology [Ann Neurol] 2026 Jul; Vol. 100 (1), pp. 123-138. Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alzheimer's Disease Co-Pathology and Cognitive Impairment in Amyotrophic Lateral Sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Kasper+E%22">Kasper E</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Lehto+A%22">Lehto A</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Jürs+A%22">Jürs A</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Nordmann+N%22">Nordmann N</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin-Institute of Psychiatry and Psychotherapy, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hellmann+J%22">Hellmann J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité - Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuropsychiatry and Laboratory of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Center for Mental Health (DZPG), Munich, Germany.; University of Edinburgh and UK DRI, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Spruth+EJ%22">Spruth EJ</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Neuropsychiatry and Laboratory of Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Petzold+GC%22">Petzold GC</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Vascular Neurology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Voigt+I%22">Voigt I</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Weydt+P%22">Weydt P</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bernsen+S%22">Bernsen S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Dinter+E%22">Dinter E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Falkenburger+B%22">Falkenburger B</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+R%22">Günther R</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University, Magdeburg, Germany.; Institute of Cognitive Neuroscience, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Glanz+W%22">Glanz W</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto-von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Synofzik+M%22">Synofzik M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division of Translational Genomics of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Beichert+L%22">Beichert L</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Division of Translational Genomics of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Spottke+A%22">Spottke A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Brosseron+F%22">Brosseron F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schmid+MC%22">Schmid MC</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Halle+A%22">Halle A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neuropathology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Herms+J%22">Herms J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Department of Neurology, University Hospital of Munich, Ludwig-Maximilians-Universität (LMU) Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department for Cognitive Disorders and Old Age Psychiatry, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Teipel+S%22">Teipel S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Prudlo+J%22">Prudlo J</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Neumann+M%22">Neumann M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Neuropathology, Tübingen University Hospital, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hermann+A%22">Hermann A</searchLink>; Department of Neurology, Rostock University Medical Center, Rostock, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, Germany.; Translational Neurodegeneration Section 'Albrecht-Kossel,' Department of Neurology, Rostock University Medical Center, Rostock, Germany.
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