A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.

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Title: A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.
Authors: Zhang Q; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌., Niu D; Guangzhou National Laboratory, Guangzhou, China., Jia Y; Guangzhou National Laboratory, Guangzhou, China., Lu L; Guangzhou National Laboratory, Guangzhou, China.; Graduate School of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China., Wu W; Guangzhou National Laboratory, Guangzhou, China., Qu C; Guangzhou National Laboratory, Guangzhou, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China., Sun Z; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China., Li S; Guangzhou National Laboratory, Guangzhou, China.; College of Life Sciences, Nankai University, Tianjin, China., Liu Z; Institute of Pathogenic Biology, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China., Lv J; Institute of Health Inspection and Testing, Hubei Provincial Centre for Disease Control and Prevention (Hubei CDC), Wuhan, China., Wang W; SCIEX, Beijing, China., Yu J; Guangzhou National Laboratory, Guangzhou, China., Zhang L; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Li C; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌., Peng W; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Zhang Q; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Wei S; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.
Source: PLoS pathogens [PLoS Pathog] 2026 May 11; Vol. 22 (5), pp. e1013741. Date of Electronic Publication: 2026 May 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7374
DOI:10.1371/journal.ppat.1013741