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A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.

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Title: A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.
Authors: Zhang Q; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌., Niu D; Guangzhou National Laboratory, Guangzhou, China., Jia Y; Guangzhou National Laboratory, Guangzhou, China., Lu L; Guangzhou National Laboratory, Guangzhou, China.; Graduate School of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China., Wu W; Guangzhou National Laboratory, Guangzhou, China., Qu C; Guangzhou National Laboratory, Guangzhou, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China., Sun Z; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China., Li S; Guangzhou National Laboratory, Guangzhou, China.; College of Life Sciences, Nankai University, Tianjin, China., Liu Z; Institute of Pathogenic Biology, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China., Lv J; Institute of Health Inspection and Testing, Hubei Provincial Centre for Disease Control and Prevention (Hubei CDC), Wuhan, China., Wang W; SCIEX, Beijing, China., Yu J; Guangzhou National Laboratory, Guangzhou, China., Zhang L; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Li C; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌., Peng W; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Zhang Q; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China., Wei S; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.
Source: PLoS pathogens [PLoS Pathog] 2026 May 11; Vol. 22 (5), pp. e1013741. Date of Electronic Publication: 2026 May 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌.<br /><searchLink fieldCode="AU" term="%22Niu+D%22">Niu D</searchLink>; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jia+Y%22">Jia Y</searchLink>; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lu+L%22">Lu L</searchLink>; Guangzhou National Laboratory, Guangzhou, China.; Graduate School of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Qu+C%22">Qu C</searchLink>; Guangzhou National Laboratory, Guangzhou, China.; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.<br /><searchLink fieldCode="AU" term="%22Sun+Z%22">Sun Z</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Guangzhou National Laboratory, Guangzhou, China.; College of Life Sciences, Nankai University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Institute of Pathogenic Biology, School of Basic Medical Sciences, Hengyang Medical School, University of South China, Hengyang, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Lv+J%22">Lv J</searchLink>; Institute of Health Inspection and Testing, Hubei Provincial Centre for Disease Control and Prevention (Hubei CDC), Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; SCIEX, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, China‌‌.<br /><searchLink fieldCode="AU" term="%22Peng+W%22">Peng W</searchLink>; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wei+S%22">Wei S</searchLink>; State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.; Guangzhou National Laboratory, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 May 11; Vol. 22 (5), pp. e1013741. <i>Date of Electronic Publication: </i>2026 May 11 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE
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