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Glucocorticoid excess disrupts NAD+ homeostasis in male and female mice.

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Title: Glucocorticoid excess disrupts NAD+ homeostasis in male and female mice.
Authors: Heaselgrave SR; Center of Hypothalamic Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Heising S; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Deng M; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK., Morgan SA; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Carthwright DM; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Ludwig C; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Rodrigues RN; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Aldiss P; Nottingham Digestive Diseases Centre, Translational Medical Sciences, and The Biodiscovery Institute, University of Nottingham, Nottingham, UK., Treebak JT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tsintzas K; MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK., Lavery GG; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK., Doig CL; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.
Source: The Journal of endocrinology [J Endocrinol] 2026 May 22; Vol. 269 (2). Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: BioScientifica Country of Publication: England NLM ID: 0375363 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1479-6805 (Electronic) Linking ISSN: 00220795 NLM ISO Abbreviation: J Endocrinol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glucocorticoid excess disrupts NAD+ homeostasis in male and female mice.
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  Data: <searchLink fieldCode="AU" term="%22Heaselgrave+SR%22">Heaselgrave SR</searchLink>; Center of Hypothalamic Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Heising+S%22">Heising S</searchLink>; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Deng+M%22">Deng M</searchLink>; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+SA%22">Morgan SA</searchLink>; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Carthwright+DM%22">Carthwright DM</searchLink>; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ludwig+C%22">Ludwig C</searchLink>; Metabolism and Systems Sciences, School of Medical Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Rodrigues+RN%22">Rodrigues RN</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Aldiss+P%22">Aldiss P</searchLink>; Nottingham Digestive Diseases Centre, Translational Medical Sciences, and The Biodiscovery Institute, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Treebak+JT%22">Treebak JT</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tsintzas+K%22">Tsintzas K</searchLink>; MRC Versus Arthritis Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Lavery+GG%22">Lavery GG</searchLink>; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Doig+CL%22">Doig CL</searchLink>; Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, UK.
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  Data: <searchLink fieldCode="JN" term="%220375363%22">The Journal of endocrinology</searchLink> [J Endocrinol] 2026 May 22; Vol. 269 (2). <i>Date of Electronic Publication: </i>2026 May 22 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioScientifica%22">BioScientifica </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0375363 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-6805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200220795%22">00220795 </searchLink><i>NLM ISO Abbreviation: </i>J Endocrinol <i>Subsets: </i>MEDLINE
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              Text: 2026 May 22
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