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Ventricular conduction is a marker for arrhythmic risk in SCN5A-E1784K overlap sodium channel disease.

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Title: Ventricular conduction is a marker for arrhythmic risk in SCN5A-E1784K overlap sodium channel disease.
Authors: Tanck MWT; Amsterdam UMC, University of Amsterdam, Epidemiology and Data Science, Amsterdam Public Health, Meibergdreef 9, Amsterdam, Netherlands., Wijeyeratne YD; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK., Barc J; Department of Medical Genetics, Nantes Université, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France., Muir A; Belfast Health and Social Care Trust, Belfast, UK., Aiba T; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan., Bos JM; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA., Veltmann C; Center of Electrophysiology Bremen, Bremen, Germany., Galvin J; Mater Misericordiae University Hospital, Dublin, Ireland., Crotti L; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Ishikawa T; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan., Ohno S; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.; Shiga University of Medical Science, Shiga, Japan., Page SP; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Denjoy I; AP-HP Nord, Hôpital Bichat, Cardiology Department and Reference Center for Hereditary Arrhythmic Diseases, Paris Cité University, INSERM U1166, Paris, France., Tester DJ; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA., Muggenthaler M; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK., Takahashi K; Kizawa Memorial Hospital, Gifu, Japan., Raju H; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.; Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia., Gourraud JB; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France., Redon R; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France., Schott JJ; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France., Haglund-Turnquist C; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA., Pedrazzini M; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy., Alberio C; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy., Dagradi F; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy., Papadakis M; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK., Sharma S; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK., Petzer E; Darent Valley Hospital, Dartford and Gravesham NHS Trust, Dartford, UK., Roden DM; Vanderbilt University School of Medicine, Nashville, USA., Horie M; Shiga University of Medical Science, Shiga, Japan., Schwartz PJ; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy., Makita N; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.; Sapporo Teishinkai Hospital, Sapporo, Japan., Borggrefe MM; Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, European Center for AngioScience (ECAS), and DZHK (German Center for Cardiovascular Research) Partner Site Heidelberg/Mannheim, Mannheim, Germany., Ackerman MJ; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA., Shimizu W; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan., McKeown PP; Belfast Health and Social Care Trust, Belfast, UK.; Queen's University Belfast, Belfast, UK., Probst V; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France., Behr ER; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.
Source: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2026 Jun 02; Vol. 28 (6).
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883649 Publication Model: Print Cited Medium: Internet ISSN: 1532-2092 (Electronic) Linking ISSN: 10995129 NLM ISO Abbreviation: Europace Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ventricular conduction is a marker for arrhythmic risk in SCN5A-E1784K overlap sodium channel disease.
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  Data: <searchLink fieldCode="AU" term="%22Tanck+MWT%22">Tanck MWT</searchLink>; Amsterdam UMC, University of Amsterdam, Epidemiology and Data Science, Amsterdam Public Health, Meibergdreef 9, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wijeyeratne+YD%22">Wijeyeratne YD</searchLink>; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Barc+J%22">Barc J</searchLink>; Department of Medical Genetics, Nantes Université, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France.<br /><searchLink fieldCode="AU" term="%22Muir+A%22">Muir A</searchLink>; Belfast Health and Social Care Trust, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Aiba+T%22">Aiba T</searchLink>; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Bos+JM%22">Bos JM</searchLink>; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Veltmann+C%22">Veltmann C</searchLink>; Center of Electrophysiology Bremen, Bremen, Germany.<br /><searchLink fieldCode="AU" term="%22Galvin+J%22">Galvin J</searchLink>; Mater Misericordiae University Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Crotti+L%22">Crotti L</searchLink>; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ishikawa+T%22">Ishikawa T</searchLink>; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ohno+S%22">Ohno S</searchLink>; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.; Shiga University of Medical Science, Shiga, Japan.<br /><searchLink fieldCode="AU" term="%22Page+SP%22">Page SP</searchLink>; Leeds Teaching Hospitals NHS Trust, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Denjoy+I%22">Denjoy I</searchLink>; AP-HP Nord, Hôpital Bichat, Cardiology Department and Reference Center for Hereditary Arrhythmic Diseases, Paris Cité University, INSERM U1166, Paris, France.<br /><searchLink fieldCode="AU" term="%22Tester+DJ%22">Tester DJ</searchLink>; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Muggenthaler+M%22">Muggenthaler M</searchLink>; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.; Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Kizawa Memorial Hospital, Gifu, Japan.<br /><searchLink fieldCode="AU" term="%22Raju+H%22">Raju H</searchLink>; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.; Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Gourraud+JB%22">Gourraud JB</searchLink>; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France.<br /><searchLink fieldCode="AU" term="%22Redon+R%22">Redon R</searchLink>; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France.<br /><searchLink fieldCode="AU" term="%22Schott+JJ%22">Schott JJ</searchLink>; Nantes Université, CHU Nantes, CNRS, INSERM, L'institut du Thorax, Nantes F-44000, France.<br /><searchLink fieldCode="AU" term="%22Haglund-Turnquist+C%22">Haglund-Turnquist C</searchLink>; Departments of Cardiovascular Medicine (Division of Heart Rhythm Services), Pediatric and Adolescent Medicine (Division of Pediatric Cardiology), and Molecular Pharmacology & Experimental Therapeutics (Windland Smith Rice Sudden Death Genomics Laboratory), Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pedrazzini+M%22">Pedrazzini M</searchLink>; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Alberio+C%22">Alberio C</searchLink>; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dagradi+F%22">Dagradi F</searchLink>; Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Papadakis+M%22">Papadakis M</searchLink>; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Sharma+S%22">Sharma S</searchLink>; Cardiovascular and Genomics Research Institute, School of Health and Medical Sciences, City St George's University of London, London SW17 0RE, UK.; St George's University Hospitals National Health Service (NHS) Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Petzer+E%22">Petzer E</searchLink>; Darent Valley Hospital, Dartford and Gravesham NHS Trust, Dartford, UK.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; 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