SSTNIV, a syndecan-1-targeting peptide chimera, reverses immune suppression and inhibits myeloma progression.

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Title: SSTNIV, a syndecan-1-targeting peptide chimera, reverses immune suppression and inhibits myeloma progression.
Authors: Jung O; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA. ojung@unmc.edu.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. ojung@unmc.edu.; Department of Human Oncology and School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA. ojung@unmc.edu., Beauvais DM; Department of Human Oncology and School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; Norcliffe Foundation Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA., Ibaan GL; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Wooldrik CC; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., Flietner E; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA., Choi S; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA. schoi@unmc.edu.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. schoi@unmc.edu., Zhang J; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA., Rapraeger AC; Department of Human Oncology and School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 May 12; Vol. 11 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2059-3635
DOI:10.1038/s41392-026-02709-1