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Rv1983 promotes mycobacterial dissemination by triggering ferroptosis through GPX4 ubiquitination.

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Title: Rv1983 promotes mycobacterial dissemination by triggering ferroptosis through GPX4 ubiquitination.
Authors: Qu Z; Hubei Province and Key Laboratory of Skin Infection and Immunity, Wuhan No. 1 Hospital, Wuhan, 430022, China.; Department of Dermatology, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhou Y; Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Cai Q; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China., Chen T; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China., Xiang Y; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China. xiangyun5272008@163.com.; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China. xiangyun5272008@163.com., Chen L; Hubei Province and Key Laboratory of Skin Infection and Immunity, Wuhan No. 1 Hospital, Wuhan, 430022, China. chlq35@126.com.; Department of Dermatology, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. chlq35@126.com., Yuan C; Department of Laboratory Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, China. chunhuii.yuen@whu.edu.cn.; Institute of Clinical Molecular Diagnosis, Wuhan University, Wuhan, 430060, China. chunhuii.yuen@whu.edu.cn.
Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2026 May 11; Vol. 31 (1). Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rv1983 promotes mycobacterial dissemination by triggering ferroptosis through GPX4 ubiquitination.
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  Data: <searchLink fieldCode="AU" term="%22Qu+Z%22">Qu Z</searchLink>; Hubei Province and Key Laboratory of Skin Infection and Immunity, Wuhan No. 1 Hospital, Wuhan, 430022, China.; Department of Dermatology, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.<br /><searchLink fieldCode="AU" term="%22Cai+Q%22">Cai Q</searchLink>; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China.<br /><searchLink fieldCode="AU" term="%22Xiang+Y%22">Xiang Y</searchLink>; Department of Laboratory Medicine, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China. xiangyun5272008@163.com.; Department of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, 430065, China. xiangyun5272008@163.com.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; Hubei Province and Key Laboratory of Skin Infection and Immunity, Wuhan No. 1 Hospital, Wuhan, 430022, China. chlq35@126.com.; Department of Dermatology, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. chlq35@126.com.<br /><searchLink fieldCode="AU" term="%22Yuan+C%22">Yuan C</searchLink>; Department of Laboratory Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, China. chunhuii.yuen@whu.edu.cn.; Institute of Clinical Molecular Diagnosis, Wuhan University, Wuhan, 430060, China. chunhuii.yuen@whu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229607427%22">Cellular & molecular biology letters</searchLink> [Cell Mol Biol Lett] 2026 May 11; Vol. 31 (1). <i>Date of Electronic Publication: </i>2026 May 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607427 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1689-1392 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214258153%22">14258153 </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Biol Lett <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42115929
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        Value: 10.1186/s11658-026-00942-8
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        Text: English
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              Text: 2026 May 11
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