Oocyte vitrification reduces blastocyst yield but preserves reproductive competence in advanced maternal age patients undergoing oocyte accumulation with PGT-A.

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Title: Oocyte vitrification reduces blastocyst yield but preserves reproductive competence in advanced maternal age patients undergoing oocyte accumulation with PGT-A.
Authors: Canosa S; IVIRMA Global Research Alliance, Genera, Livet, Turin, Italy.. Electronic address: s.canosa88@gmail.com., Cimadomo D; IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy.; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia, Italy., Maggiulli R; IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy., Revelli A; IVIRMA Global Research Alliance, Genera, Livet, Turin, Italy.; Obstetrics and Gynecology 2U, Department of Surgical Sciences, City of Health and Science, S. Anna Hospital, University of Turin, Turin, Italy., Gennarelli G; IVIRMA Global Research Alliance, Genera, Livet, Turin, Italy.; Obstetrics and Gynecology 1U, Physiology of Reproduction and IVF Unit, Department of Surgical Sciences, City of Health and Science, S. Anna Hospital, University of Turin, Turin, Italy., Ottolini CS; Juno Genetics, Rome, Italy.; University College London Institute for Women's Health, Department of Maternal and Fetal Medicine, London, UK., Capalbo A; Juno Genetics, Rome, Italy.; Unit of Molecular Genetics, Center for Advanced Studies and Technology (CAST), 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy., Bongioanni F; IVIRMA Global Research Alliance, Genera, Livet, Turin, Italy., Rienzi L; IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy.; Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Urbino, Italy., Coticchio G; IVIRMA Global Research Alliance, IVIRMA Italia, Rome, Italy.
Source: Reproductive biomedicine online [Reprod Biomed Online] 2026 Jul; Vol. 53 (1), pp. 105503. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101122473 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1472-6491 (Electronic) Linking ISSN: 14726483 NLM ISO Abbreviation: Reprod Biomed Online Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1472-6491
DOI:10.1016/j.rbmo.2026.105503