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Inhibitor development according to FVIII concentrates in previously untreated patients with severe hemophilia A: update from the PedNet registry.

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Title: Inhibitor development according to FVIII concentrates in previously untreated patients with severe hemophilia A: update from the PedNet registry.
Authors: Fischer K; Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, The Netherlands; PedNet Research Foundation, Baarn, Netherlands., Olivieri M; Paediatric Thrombosis and Haemostasis Unit, Paediatric Haemophilia Center, Dr. von Hauner Children's Hospital, LMU Munich, Munich, Germany., Ranta S; Pediatric Coagulation Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Pediatric Oncology, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Pinto F; Department of Haematology, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK., Labarque V; University Hospitals Leuven, Service of Pediatric Haematology, Leuven, Belgium; KU Leuven, Department of Cardiovascular Sciences, Leuven, Belgium., Zapotocka E; Department of Pediatric Hematology and Oncology, University Hospital Motol and Homolka and Second Faculty of Medicine, Charles University, Prague, Czech Republic., Motwani J; Department of Haematology, Children's Hospital, Birmingham, UK., Kenet G; PedNet Research Foundation, Baarn, Netherlands; National Hemophilia Center, Sheba Medical Center, Tel Hashomer and Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Israel., Königs C; Goethe University, University Hospital Frankfurt, Department of Paediatrics and Adolescent Medicine, Frankfurt, Germany., Nolan B; Department of Paediatric Haematology, Children's Coagulation Centre, Children's Health Ireland at Crumlin, Dublin, Ireland., Blatný J; HCCC, Centre for Thrombosis and Haemothasis at the Department of Paediatric Haematology and Biochemistry, University Hospital Brno, Brno, Czech Republic., Carcao M; Division of Haematology/Oncology, Department of Paediatrics, Hospital for Sick Children, Toronto, Canada., Van Geet C; University Hospitals Leuven, Service of Pediatric Haematology, Leuven, Belgium; KU Leuven, Department of Cardiovascular Sciences, Leuven, Belgium., de Kovel M; PedNet Research Foundation, Baarn, Netherlands. Electronic address: m.s.dekovel@pednet.eu., Andersson NG; Department of Clinical Sciences, Lund University, Lund, Sweden; Department of Pediatrics and Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden.
Corporate Authors: PedNet Study Group
Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2026 May 12. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibitor development according to FVIII concentrates in previously untreated patients with severe hemophilia A: update from the PedNet registry.
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  Data: <searchLink fieldCode="AU" term="%22Fischer+K%22">Fischer K</searchLink>; Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Center Utrecht, Utrecht, The Netherlands; PedNet Research Foundation, Baarn, Netherlands.<br /><searchLink fieldCode="AU" term="%22Olivieri+M%22">Olivieri M</searchLink>; Paediatric Thrombosis and Haemostasis Unit, Paediatric Haemophilia Center, Dr. von Hauner Children's Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ranta+S%22">Ranta S</searchLink>; Pediatric Coagulation Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Pediatric Oncology, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Pinto+F%22">Pinto F</searchLink>; Department of Haematology, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Labarque+V%22">Labarque V</searchLink>; University Hospitals Leuven, Service of Pediatric Haematology, Leuven, Belgium; KU Leuven, Department of Cardiovascular Sciences, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Zapotocka+E%22">Zapotocka E</searchLink>; Department of Pediatric Hematology and Oncology, University Hospital Motol and Homolka and Second Faculty of Medicine, Charles University, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Motwani+J%22">Motwani J</searchLink>; Department of Haematology, Children's Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Kenet+G%22">Kenet G</searchLink>; PedNet Research Foundation, Baarn, Netherlands; National Hemophilia Center, Sheba Medical Center, Tel Hashomer and Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Israel.<br /><searchLink fieldCode="AU" term="%22Königs+C%22">Königs C</searchLink>; Goethe University, University Hospital Frankfurt, Department of Paediatrics and Adolescent Medicine, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Nolan+B%22">Nolan B</searchLink>; Department of Paediatric Haematology, Children's Coagulation Centre, Children's Health Ireland at Crumlin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Blatný+J%22">Blatný J</searchLink>; HCCC, Centre for Thrombosis and Haemothasis at the Department of Paediatric Haematology and Biochemistry, University Hospital Brno, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Carcao+M%22">Carcao M</searchLink>; Division of Haematology/Oncology, Department of Paediatrics, Hospital for Sick Children, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Van+Geet+C%22">Van Geet C</searchLink>; University Hospitals Leuven, Service of Pediatric Haematology, Leuven, Belgium; KU Leuven, Department of Cardiovascular Sciences, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22de+Kovel+M%22">de Kovel M</searchLink>; PedNet Research Foundation, Baarn, Netherlands. Electronic address: m.s.dekovel@pednet.eu.<br /><searchLink fieldCode="AU" term="%22Andersson+NG%22">Andersson NG</searchLink>; Department of Clinical Sciences, Lund University, Lund, Sweden; Department of Pediatrics and Malmö Centre for Thrombosis and Haemostasis, Skåne University Hospital, Malmö, Sweden.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101170508 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7836 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215387836%22">15387836 </searchLink><i>NLM ISO Abbreviation: </i>J Thromb Haemost <i>Subsets: </i>MEDLINE
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