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MCL1 inhibition to enhance the efficacy of MYB targeting in pediatric acute myeloid leukemia.

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Title: MCL1 inhibition to enhance the efficacy of MYB targeting in pediatric acute myeloid leukemia.
Authors: Tsakaneli A; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Che N; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Virely C; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., McCord B; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Gasparoli L; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Loe A; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK., Fung K; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK., Ciampa O; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Alver NM; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Li Q; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK., Bartram J; Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, UK., O'Connor D; Department of Haematology, Cancer Institute, University College London, London, UK.; Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, UK., Mansour M; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK., Williams O; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK. owen.williams@ucl.ac.uk.
Source: Cell death & disease [Cell Death Dis] 2026 May 13; Vol. 17 (1). Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: MCL1 inhibition to enhance the efficacy of MYB targeting in pediatric acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Tsakaneli+A%22">Tsakaneli A</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Che+N%22">Che N</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Virely+C%22">Virely C</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22McCord+B%22">McCord B</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Gasparoli+L%22">Gasparoli L</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Loe+A%22">Loe A</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Fung+K%22">Fung K</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ciampa+O%22">Ciampa O</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Alver+NM%22">Alver NM</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Bartram+J%22">Bartram J</searchLink>; Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22O'Connor+D%22">O'Connor D</searchLink>; Department of Haematology, Cancer Institute, University College London, London, UK.; Department of Paediatric Haematology, Great Ormond Street Hospital for Children, London, UK.<br /><searchLink fieldCode="AU" term="%22Mansour+M%22">Mansour M</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK.; Department of Haematology, Cancer Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Williams+O%22">Williams O</searchLink>; Cancer Section, Developmental Biology and Cancer Department, UCL Great Ormond Street Institute of Child Health, London, UK. owen.williams@ucl.ac.uk.
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