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Cell Cycle Dysfunction and Metabolic Alterations Consistent With Pathological Tau in Progressive Supranuclear Palsy Derived Fibroblasts.

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Title: Cell Cycle Dysfunction and Metabolic Alterations Consistent With Pathological Tau in Progressive Supranuclear Palsy Derived Fibroblasts.
Authors: De Mori R; Induced Pluripotent Stem Cells and Organoids Unit IRCCS Santa Lucia Foundation, Via Ardeatina 306-354, Rome, 00179, Italy., Ciaiola F; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.; Dipartimento Delle Scienze Mediche, Università Degli Studi Di Napoli 'Parthenope', Motorie E del Benessere, Naples, Italy., Nesci V; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy., Gimenez J; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy., de Bardi M; Neuroimmunology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Pieroni L; Departmental Faculty of Medicine and Surgery, UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.; IRCCS San Camillo Hospital, Venice, Italy., de Stefano S; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.; Unit of Clinical Biochemistry, Fondazione PTV - Tor Vergata University Hospital, Rome, Italy., Borsellino G; Neuroimmunology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Valle C; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), Rome, Italy., Ferri A; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), Rome, Italy., Stefani A; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy., Mascioli D; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy., Mancini M; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy., Mercuri NB; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.; Experimental Neurology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Spalloni A; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy., Schirinzi T; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy., Longone P; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy. p.longone@hsantalucia.it.
Source: Molecular neurobiology [Mol Neurobiol] 2026 May 12; Vol. 63 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cell Cycle Dysfunction and Metabolic Alterations Consistent With Pathological Tau in Progressive Supranuclear Palsy Derived Fibroblasts.
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  Data: <searchLink fieldCode="AU" term="%22De+Mori+R%22">De Mori R</searchLink>; Induced Pluripotent Stem Cells and Organoids Unit IRCCS Santa Lucia Foundation, Via Ardeatina 306-354, Rome, 00179, Italy.<br /><searchLink fieldCode="AU" term="%22Ciaiola+F%22">Ciaiola F</searchLink>; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.; Dipartimento Delle Scienze Mediche, Università Degli Studi Di Napoli 'Parthenope', Motorie E del Benessere, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Nesci+V%22">Nesci V</searchLink>; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gimenez+J%22">Gimenez J</searchLink>; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.<br /><searchLink fieldCode="AU" term="%22de+Bardi+M%22">de Bardi M</searchLink>; Neuroimmunology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pieroni+L%22">Pieroni L</searchLink>; Departmental Faculty of Medicine and Surgery, UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.; IRCCS San Camillo Hospital, Venice, Italy.<br /><searchLink fieldCode="AU" term="%22de+Stefano+S%22">de Stefano S</searchLink>; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.; Unit of Clinical Biochemistry, Fondazione PTV - Tor Vergata University Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Borsellino+G%22">Borsellino G</searchLink>; Neuroimmunology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Valle+C%22">Valle C</searchLink>; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ferri+A%22">Ferri A</searchLink>; Neurochemistry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.; Institute of Translational Pharmacology (IFT), National Research Council (CNR), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Stefani+A%22">Stefani A</searchLink>; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mascioli+D%22">Mascioli D</searchLink>; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mancini+M%22">Mancini M</searchLink>; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mercuri+NB%22">Mercuri NB</searchLink>; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.; Experimental Neurology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Spalloni+A%22">Spalloni A</searchLink>; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy.<br /><searchLink fieldCode="AU" term="%22Schirinzi+T%22">Schirinzi T</searchLink>; Unit of Neurology, Department of Systems Medicine, Fondazione PTV - Tor Vergata University Hospital, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Longone+P%22">Longone P</searchLink>; Molecular Neurobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, 00147, Italy. p.longone@hsantalucia.it.
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  Data: <searchLink fieldCode="JN" term="%228900963%22">Molecular neurobiology</searchLink> [Mol Neurobiol] 2026 May 12; Vol. 63 (1). <i>Date of Electronic Publication: </i>2026 May 12.
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