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A comparative analysis in a clinical cohort: multiple imputation by chained equations and a novel super learner-based imputation approach.

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Title: A comparative analysis in a clinical cohort: multiple imputation by chained equations and a novel super learner-based imputation approach.
Authors: Zbysinski T; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA. tony.zbysinski@refinedscience.com., Wu L; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Dale J; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Coates J; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Sapiah K; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Reuben J; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Markson F; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Kulkarni U; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA., Islam N; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.
Source: BMC medical research methodology [BMC Med Res Methodol] 2026 May 12; Vol. 26 (1). Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968545 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2288 (Electronic) Linking ISSN: 14712288 NLM ISO Abbreviation: BMC Med Res Methodol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Zbysinski+T%22">Zbysinski T</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA. tony.zbysinski@refinedscience.com.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Dale+J%22">Dale J</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Coates+J%22">Coates J</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Sapiah+K%22">Sapiah K</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Reuben+J%22">Reuben J</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Markson+F%22">Markson F</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Kulkarni+U%22">Kulkarni U</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Islam+N%22">Islam N</searchLink>; RefinedScience, 2115 N Scranton Street, Suite 2-70, Aurora, Colorado, 80045, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100968545 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712288%22">14712288 </searchLink><i>NLM ISO Abbreviation: </i>BMC Med Res Methodol <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12874-026-02858-5
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        Text: English
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              M: 05
              Text: 2026 May 12
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