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Novel NSAID Analogs Exhibit Anti-Leukemic Activity Through Modulation of Apoptotic and Survival Pathways.

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Title: Novel NSAID Analogs Exhibit Anti-Leukemic Activity Through Modulation of Apoptotic and Survival Pathways.
Authors: Alkhatabi HA; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia., Basabrain M; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alahmadi AG; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia., Alzahrani SM; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Muhammad YA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia., Almuhaiyawi M; Collage of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah 22384, Saudi Arabia., Alreemi MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alotibi RM; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia., Alreemi RM; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia., Alkhattabi HA; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Hassan RN; Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Al-Bishri WM; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia., El-Mezgueldi M; Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Room3/28a, London SE1 1UL, UK.; College of Health and Life Sciences, School of Biosciences, University of Aston, Birmingham B4 7ET, UK., Omar AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Apr 26; Vol. 27 (9). Date of Electronic Publication: 2026 Apr 26.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel NSAID Analogs Exhibit Anti-Leukemic Activity Through Modulation of Apoptotic and Survival Pathways.
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  Data: <searchLink fieldCode="AU" term="%22Alkhatabi+HA%22">Alkhatabi HA</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Basabrain+M%22">Basabrain M</searchLink>; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alahmadi+AG%22">Alahmadi AG</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alzahrani+SM%22">Alzahrani SM</searchLink>; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Muhammad+YA%22">Muhammad YA</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almuhaiyawi+M%22">Almuhaiyawi M</searchLink>; Collage of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah 22384, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alreemi+MM%22">Alreemi MM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alotibi+RM%22">Alotibi RM</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alreemi+RM%22">Alreemi RM</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alkhattabi+HA%22">Alkhattabi HA</searchLink>; Institute of Genomic Medicine Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hassan+RN%22">Hassan RN</searchLink>; Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Bishri+WM%22">Al-Bishri WM</searchLink>; Department of Biological Sciences, College of Science, University of Jeddah, Jeddah 21956, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22El-Mezgueldi+M%22">El-Mezgueldi M</searchLink>; Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Room3/28a, London SE1 1UL, UK.; College of Health and Life Sciences, School of Biosciences, University of Aston, Birmingham B4 7ET, UK.<br /><searchLink fieldCode="AU" term="%22Omar+AM%22">Omar AM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia.
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              Text: 2026 Apr 26
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