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A Hidden Binding Pocket in the β- ketoacyl-ACP Synthase FabB.

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Title: A Hidden Binding Pocket in the β- ketoacyl-ACP Synthase FabB.
Authors: Jiang Z; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr., La Jolla, California, 92093, United States., Friedman A; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States., Thompson A; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States., Andrzejewski SJ; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States., Mains K; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States., Sankaran B; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, United States., Burkart MD; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr., La Jolla, California, 92093, United States., Shirts MR; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States., Fox JM; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 28. Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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An: 42124610
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PubType: Academic Journal
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  Data: <searchLink fieldCode="AU" term="%22Jiang+Z%22">Jiang Z</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr., La Jolla, California, 92093, United States.<br /><searchLink fieldCode="AU" term="%22Friedman+A%22">Friedman A</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.<br /><searchLink fieldCode="AU" term="%22Thompson+A%22">Thompson A</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.<br /><searchLink fieldCode="AU" term="%22Andrzejewski+SJ%22">Andrzejewski SJ</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.<br /><searchLink fieldCode="AU" term="%22Mains+K%22">Mains K</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.<br /><searchLink fieldCode="AU" term="%22Sankaran+B%22">Sankaran B</searchLink>; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, 94720, United States.<br /><searchLink fieldCode="AU" term="%22Burkart+MD%22">Burkart MD</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr., La Jolla, California, 92093, United States.<br /><searchLink fieldCode="AU" term="%22Shirts+MR%22">Shirts MR</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.<br /><searchLink fieldCode="AU" term="%22Fox+JM%22">Fox JM</searchLink>; Department of Chemical and Biological Engineering, University of Colorado, Boulder, 3415 Colorado Avenue, Boulder, Colorado, 80303, United States.
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        Value: 10.64898/2026.02.26.708327
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        Text: English
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              Text: 2026 Feb 28
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