Local GPCR density tips the balance of μ-opioid receptor trafficking.
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| Title: | Local GPCR density tips the balance of μ-opioid receptor trafficking. |
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| Authors: | Holsey MD; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; These authors contributed equally., Bondar A; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, USA.; Current affiliation: Institute of Plant Molecular Biology, Biology Centre of the Czech Academy of Sciences; Department of Molecular Biology and Genetics, Faculty of Science, University of South Bohemia CZ - 37005, České Budějovice, Czech Republic., Geggier P; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Dukas GV; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA., Webb CM; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Govindaraju A; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Current affiliation: Plant and Microbial Biology Program, University of California, Berkeley, Berkeley, California, USA., Mathiasen S; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Current affiliation: Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Canals M; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.; Centre of Membrane Proteins and Receptors, Universities of Nottingham and Birmingham, Midlands, UK., Lambert NA; Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, USA., Asher WB; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; These authors contributed equally., Javitch JA; Department of Physiology and Cellular Biophysics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Lead contact. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 28. Date of Electronic Publication: 2026 Feb 28. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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