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Predictable clonal hierarchies from restricted progenitors provide a framework for cell type-specific therapies in glioblastoma.

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Title: Predictable clonal hierarchies from restricted progenitors provide a framework for cell type-specific therapies in glioblastoma.
Authors: Fazzari E; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Azizad DJ; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Li MX; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Ge W; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Baisiwala S; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Cadet D; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Nano PR; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Kan RL; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Perryman T; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Tum HA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Tse C; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Wick B; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA., Arguelles CV; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Patel KS; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Liau LM; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Prins RM; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA., Nathanson DA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Bhaduri A; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 23. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Predictable clonal hierarchies from restricted progenitors provide a framework for cell type-specific therapies in glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Fazzari+E%22">Fazzari E</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Azizad+DJ%22">Azizad DJ</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+MX%22">Li MX</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ge+W%22">Ge W</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Baisiwala+S%22">Baisiwala S</searchLink>; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cadet+D%22">Cadet D</searchLink>; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nano+PR%22">Nano PR</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kan+RL%22">Kan RL</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Perryman+T%22">Perryman T</searchLink>; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tum+HA%22">Tum HA</searchLink>; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tse+C%22">Tse C</searchLink>; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wick+B%22">Wick B</searchLink>; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.<br /><searchLink fieldCode="AU" term="%22Arguelles+CV%22">Arguelles CV</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Patel+KS%22">Patel KS</searchLink>; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liau+LM%22">Liau LM</searchLink>; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Prins+RM%22">Prins RM</searchLink>; Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nathanson+DA%22">Nathanson DA</searchLink>; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bhaduri+A%22">Bhaduri A</searchLink>; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, Los Angeles, CA, USA.
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