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Advances in PARP Inhibition in Improving Outcomes of Breast Cancer, Ovarian Cancer, and Other Solid Tumors: Journey of Discovery, Development, and Clinical Updates of Talazoparib.

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Title: Advances in PARP Inhibition in Improving Outcomes of Breast Cancer, Ovarian Cancer, and Other Solid Tumors: Journey of Discovery, Development, and Clinical Updates of Talazoparib.
Authors: Latif M; Centre for Genetics and Inherited Diseases (CGID), Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.; Division of Biochemistry and Molecular Biology, Department of Basic Medical Sciences, College of Medicine, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.; Department of Chemistry, Rawalpindi Women University, Rawalpindi, 46300, Pakistan., Mazhar S; Mirpur University of Science and Technology (MUST), Mirpur, Azad Jammu and Kashmir (AJK), 10250, Pakistan.; Department of Chemistry, School of Natural Sciences (SNS), National University of Sciences and Technology (NUST), H-12, Islamabad, 44000 Pakistan., Tasleem M; Department of Chemistry and Chemical Engineering, Lahore University of Management Sciences, Lahore, Pakistan., Alqurashi A; Department of Biology, College of Science, Taibah University, Medinah, 42353‎, Kingdom of Saudi Arabia., Arfan M; Department of Chemistry, School of Natural Sciences (SNS), National University of Sciences and Technology (NUST), Islamabad, 44000, Pakistan., Ashraf Z; Department of Chemistry, Rawalpindi Women University, Rawalpindi, 46300, Pakistan., Zafar MS; Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.; Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.; School of Dentistry, Jordan University, Amman, Jordan.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 May 06; Vol. 20, pp. 575152. Date of Electronic Publication: 2026 May 06 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Advances in PARP Inhibition in Improving Outcomes of Breast Cancer, Ovarian Cancer, and Other Solid Tumors: Journey of Discovery, Development, and Clinical Updates of Talazoparib.
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  Data: <searchLink fieldCode="AU" term="%22Latif+M%22">Latif M</searchLink>; Centre for Genetics and Inherited Diseases (CGID), Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.; Division of Biochemistry and Molecular Biology, Department of Basic Medical Sciences, College of Medicine, Taibah University, Madinah, 42353, Kingdom of Saudi Arabia.; Department of Chemistry, Rawalpindi Women University, Rawalpindi, 46300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Mazhar+S%22">Mazhar S</searchLink>; Mirpur University of Science and Technology (MUST), Mirpur, Azad Jammu and Kashmir (AJK), 10250, Pakistan.; Department of Chemistry, School of Natural Sciences (SNS), National University of Sciences and Technology (NUST), H-12, Islamabad, 44000 Pakistan.<br /><searchLink fieldCode="AU" term="%22Tasleem+M%22">Tasleem M</searchLink>; Department of Chemistry and Chemical Engineering, Lahore University of Management Sciences, Lahore, Pakistan.<br /><searchLink fieldCode="AU" term="%22Alqurashi+A%22">Alqurashi A</searchLink>; Department of Biology, College of Science, Taibah University, Medinah, 42353‎, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Arfan+M%22">Arfan M</searchLink>; Department of Chemistry, School of Natural Sciences (SNS), National University of Sciences and Technology (NUST), Islamabad, 44000, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ashraf+Z%22">Ashraf Z</searchLink>; Department of Chemistry, Rawalpindi Women University, Rawalpindi, 46300, Pakistan.<br /><searchLink fieldCode="AU" term="%22Zafar+MS%22">Zafar MS</searchLink>; Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.; Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.; School of Dentistry, Jordan University, Amman, Jordan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Dove+Press+Limited%22">Dove Press Limited </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101475745 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1177-8881 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211778881%22">11778881 </searchLink><i>NLM ISO Abbreviation: </i>Drug Des Devel Ther <i>Subsets: </i>MEDLINE
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        Value: 10.2147/DDDT.S575152
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        Text: English
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              Text: 2026 May 06
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