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Novel insights into early Alzheimer's disease: quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology.

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Title: Novel insights into early Alzheimer's disease: quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology.
Authors: Kothapalli SVVN; Department of Radiology Washington University in St. Louis St. Louis Missouri USA., Benzinger TLS; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA., Bateman RJ; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.; Tracy Family SILQ Center Washington University in St. Louis St. Louis Missouri USA., Li M; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.; Tracy Family SILQ Center Washington University in St. Louis St. Louis Missouri USA., Eldeniz C; Department of Radiology Washington University in St. Louis St. Louis Missouri USA., Morris JC; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.; Department of Neurology Washington University in St. Louis St. Louis Missouri USA., Yablonskiy DA; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.
Source: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2026 May 10; Vol. 18, pp. e70355. Date of Electronic Publication: 2026 May 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101654604 Publication Model: eCollection Cited Medium: Print ISSN: 2352-8729 (Print) Linking ISSN: 23528729 NLM ISO Abbreviation: Alzheimers Dement (Amst) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel insights into early Alzheimer's disease: quantitative gradient recalled echo MRI reveals preatrophic neuronal and myelin injury concurrent with emerging amyloid pathology.
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  Data: <searchLink fieldCode="AU" term="%22Kothapalli+SVVN%22">Kothapalli SVVN</searchLink>; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.; Tracy Family SILQ Center Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.; Tracy Family SILQ Center Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Eldeniz+C%22">Eldeniz C</searchLink>; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.; Department of Neurology Washington University in St. Louis St. Louis Missouri USA.<br /><searchLink fieldCode="AU" term="%22Yablonskiy+DA%22">Yablonskiy DA</searchLink>; Department of Radiology Washington University in St. Louis St. Louis Missouri USA.; Knight Alzheimer Disease Research Center Washington University in St. Louis St. Louis Missouri USA.; The Hope Center for Neurological Disorders Washington University in St. Louis St. Louis Missouri USA.
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  Data: <searchLink fieldCode="JN" term="%22101654604%22">Alzheimer's & dementia (Amsterdam, Netherlands)</searchLink> [Alzheimers Dement (Amst)] 2026 May 10; Vol. 18, pp. e70355. <i>Date of Electronic Publication: </i>2026 May 10 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+on+behalf+of+the+Alzheimer's+Association%22">Wiley on behalf of the Alzheimer's Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101654604 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2352-8729 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223528729%22">23528729 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement (Amst) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1002/dad2.70355
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        Text: English
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              Text: 2026 May 10
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