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Targeting Cancer Cachexia: A Mechanistic Evaluation of Anti-GDF-15 Antibody-Based Combination Therapies.

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Title: Targeting Cancer Cachexia: A Mechanistic Evaluation of Anti-GDF-15 Antibody-Based Combination Therapies.
Authors: Breen DM; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Joaquim S; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Paulhus BL; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Bennett D; Biostatistics, Early Clinical Development, Pfizer Inc, Cambridge, Massachusetts, USA., Bernardo B; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Collins S; Statistics, Internal Medicine Research Unit, Pfizer R&D UK Limited, Cambridge, UK., Esquejo RM; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Kim-Muller JY; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Lin L; Biomedicine Design, Pfizer Inc, Cambridge, Massachusetts, USA., Peloquin M; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Wu Z; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Qiao S; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Stansfield JC; Biostatistics, Early Clinical Development, Pfizer Inc, Cambridge, Massachusetts, USA., Zhang BB; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA., Rossulek MI; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70312.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101552883%22">Journal of cachexia, sarcopenia and muscle</searchLink> [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70312.
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        Value: 10.1002/jcsm.70312
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              Text: 2026 Jun
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