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Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability.

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Title: Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability.
Authors: Zhao X; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Clinical Laboratory, Guizhou Provincial People's Hospital, Guiyang, Guizhou, People's Republic of China., Wang X; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Liu K; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Fang Q; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Wang C; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Mei G; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Qu L; School of Basic Medical Sciences, Hubei University of Science and Technology, Xianning, Hubei, People's Republic of China., Zhang J; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Feng J; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Yang W; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Zhu J; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Zhuo H; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Kuang N; Ecological Station of Oncomelania Hupensis in Gong'an County, Jingzhou, Hubei, People's Republic of China., Qiu X; Wuhan Kindstar Diagnostics Co Ltd, Wuhan, Hubei, People's Republic of China., Deng Z; Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Provincial Clinical Research Center for Natural Polymer Biological Liver, Wuhan, Hubei, People's Republic of China., Luo Q; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China., Jin X; Department of Parasitology, Bengbu Medical University, Bengbu, Anhui, People's Republic of China., Jiang L; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Li X; Center for Stem Cell Research and Application, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China., Dong H; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China., Zhou R; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
Source: PLoS pathogens [PLoS Pathog] 2026 May 13; Vol. 22 (5), pp. e1014007. Date of Electronic Publication: 2026 May 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Clinical Laboratory, Guizhou Provincial People's Hospital, Guiyang, Guizhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+K%22">Liu K</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Fang+Q%22">Fang Q</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Mei+G%22">Mei G</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Qu+L%22">Qu L</searchLink>; School of Basic Medical Sciences, Hubei University of Science and Technology, Xianning, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Feng+J%22">Feng J</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhuo+H%22">Zhuo H</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Kuang+N%22">Kuang N</searchLink>; Ecological Station of Oncomelania Hupensis in Gong'an County, Jingzhou, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Qiu+X%22">Qiu X</searchLink>; Wuhan Kindstar Diagnostics Co Ltd, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Deng+Z%22">Deng Z</searchLink>; Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Provincial Clinical Research Center for Natural Polymer Biological Liver, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Luo+Q%22">Luo Q</searchLink>; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; Department of Parasitology, Bengbu Medical University, Bengbu, Anhui, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Center for Stem Cell Research and Application, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Dong+H%22">Dong H</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhou+R%22">Zhou R</searchLink>; Hubei Province Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.; Department of Medical Parasitology, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 May 13; Vol. 22 (5), pp. e1014007. <i>Date of Electronic Publication: </i>2026 May 13 (<i>Print Publication: </i>2026).
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