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Neuroepithelial Tumor with AAV Integration after Intracisternal Magna Vector Delivery.

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Title: Neuroepithelial Tumor with AAV Integration after Intracisternal Magna Vector Delivery.
Authors: Ahrens-Nicklas RC; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Division of Medical Genetics and Genomics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Kotch C; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia., Roche AM; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Everett JK; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Reddy S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Santi M; Department of Pathology, University of Pennsylvania, Philadelphia., Madsen PJ; Department of Neurosurgery, University of Pennsylvania, Philadelphia., Martos-Rus C; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia., Yrigollen CM; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia., Small JC; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia., McCague S; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia., Davidson BL; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pathology, University of Pennsylvania, Philadelphia., Samelson-Jones BJ; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia., Surrey LF; Department of Pathology, University of Pennsylvania, Philadelphia., Li M; Department of Pathology, University of Pennsylvania, Philadelphia., Ficicioglu C; Division of Medical Genetics and Genomics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia., Wang R; Department of Pediatrics, University of California Irvine School of Medicine, Irvine., Bushman FD; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia., George LA; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia.
Source: The New England journal of medicine [N Engl J Med] 2026 Jun 04; Vol. 394 (21), pp. 2126-2133. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
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  Data: Neuroepithelial Tumor with AAV Integration after Intracisternal Magna Vector Delivery.
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  Data: <searchLink fieldCode="AU" term="%22Ahrens-Nicklas+RC%22">Ahrens-Nicklas RC</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Division of Medical Genetics and Genomics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Kotch+C%22">Kotch C</searchLink>; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Roche+AM%22">Roche AM</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Everett+JK%22">Everett JK</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Reddy+S%22">Reddy S</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Santi+M%22">Santi M</searchLink>; Department of Pathology, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Madsen+PJ%22">Madsen PJ</searchLink>; Department of Neurosurgery, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Martos-Rus+C%22">Martos-Rus C</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Yrigollen+CM%22">Yrigollen CM</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Small+JC%22">Small JC</searchLink>; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22McCague+S%22">McCague S</searchLink>; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Davidson+BL%22">Davidson BL</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pathology, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Samelson-Jones+BJ%22">Samelson-Jones BJ</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Surrey+LF%22">Surrey LF</searchLink>; Department of Pathology, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Pathology, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Ficicioglu+C%22">Ficicioglu C</searchLink>; Division of Medical Genetics and Genomics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Department of Pediatrics, University of California Irvine School of Medicine, Irvine.<br /><searchLink fieldCode="AU" term="%22Bushman+FD%22">Bushman FD</searchLink>; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.<br /><searchLink fieldCode="AU" term="%22George+LA%22">George LA</searchLink>; Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.; Clinical In Vivo Gene Therapy, Children's Hospital of Philadelphia, Philadelphia.
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  Data: <searchLink fieldCode="JN" term="%220255562%22">The New England journal of medicine</searchLink> [N Engl J Med] 2026 Jun 04; Vol. 394 (21), pp. 2126-2133. <i>Date of Electronic Publication: </i>2026 May 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Massachusetts+Medical+Society%22">Massachusetts Medical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0255562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-4406 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200284793%22">00284793 </searchLink><i>NLM ISO Abbreviation: </i>N Engl J Med <i>Subsets: </i>MEDLINE
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        Value: 10.1056/NEJMoa2601608
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      – TitleFull: Neuroepithelial Tumor with AAV Integration after Intracisternal Magna Vector Delivery.
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              Text: 2026 Jun 04
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