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Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease.

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Title: Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease.
Authors: Calleja-Conde J; Cardenal Cisneros Higher Education Center, 28006 Madrid, Spain; NBC Group, School of Life and Nature Sciences, Nebrija University, 28248 Madrid, Spain., Echeverry-Alzate V; NBC Group, School of Life and Nature Sciences, Nebrija University, 28248 Madrid, Spain., Sanz-SanCristobal M; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain., Alonso-Gil S; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain; Molecular and Cellular Biosciences 'Margarita Salas' Center for Biological Research (CIB), 28040 Madrid, Spain., Giné E; Department of Cell Biology and Histology, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain., Bühler K; Department of Psychobiology and Methodology in Behavioral Sciences, Faculty of Psychology, Complutense University of Madrid, 28223 Madrid, Spain., López-Moreno JA; Department of Psychobiology and Methodology in Behavioral Sciences, Faculty of Psychology, Complutense University of Madrid, 28223 Madrid, Spain., Perez-Castillo A; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain., Morales-García JA; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain; Department of Cell Biology and Histology, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain. Electronic address: jamorales@ucm.es.
Source: Experimental neurology [Exp Neurol] 2026 Sep; Vol. 403, pp. 115822. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE
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  Data: Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Calleja-Conde+J%22">Calleja-Conde J</searchLink>; Cardenal Cisneros Higher Education Center, 28006 Madrid, Spain; NBC Group, School of Life and Nature Sciences, Nebrija University, 28248 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Echeverry-Alzate+V%22">Echeverry-Alzate V</searchLink>; NBC Group, School of Life and Nature Sciences, Nebrija University, 28248 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sanz-SanCristobal+M%22">Sanz-SanCristobal M</searchLink>; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso-Gil+S%22">Alonso-Gil S</searchLink>; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain; Molecular and Cellular Biosciences 'Margarita Salas' Center for Biological Research (CIB), 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Giné+E%22">Giné E</searchLink>; Department of Cell Biology and Histology, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bühler+K%22">Bühler K</searchLink>; Department of Psychobiology and Methodology in Behavioral Sciences, Faculty of Psychology, Complutense University of Madrid, 28223 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Moreno+JA%22">López-Moreno JA</searchLink>; Department of Psychobiology and Methodology in Behavioral Sciences, Faculty of Psychology, Complutense University of Madrid, 28223 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Castillo+A%22">Perez-Castillo A</searchLink>; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Morales-García+JA%22">Morales-García JA</searchLink>; Institute for Biomedical Research Sols-Morreale (CSIC-UAM), 28029 Madrid, Spain; Networking Research Center on Neurodegenerative Diseases (CIBERNED), Carlos III Health Institute, 28031 Madrid, Spain; Department of Cell Biology and Histology, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain. Electronic address: jamorales@ucm.es.
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  Data: <searchLink fieldCode="JN" term="%220370712%22">Experimental neurology</searchLink> [Exp Neurol] 2026 Sep; Vol. 403, pp. 115822. <i>Date of Electronic Publication: </i>2026 May 12.
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