Randomized controlled trial of vericiguat in patients with coronary microvascular dysfunction causing stable chest pain (V-COM): study protocol for a randomized control trial.

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Title: Randomized controlled trial of vericiguat in patients with coronary microvascular dysfunction causing stable chest pain (V-COM): study protocol for a randomized control trial.
Authors: Lo CK; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Ip NH; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Sin TH; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Ho SY; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Wong CK; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Tam FC; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Lam SC; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Yiu KH; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China., Sze MS; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Lam TT; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Chiu ACH; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Li KK; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Un KC; Department of Medicine, Queen Mary Hospital, Hong Kong, China., Yu EY; Department of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong, China., Chan EK; Department of Medicine, Grantham Hospital, United Kingdom., Lee KK; Department of Medicine and Geriatrics, Ruttonjee and Tang Shiu Kin Hospitals, Hong Kong, China., Ching S; Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China., Lee DP; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China., Wong CY; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China., Chan HL; Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China., Chan NY; Department of Medicine & Geriatrics, Princess Margaret Hospital, Hong Kong, China., Leung CY; Department of Medicine, Tseung Kwan O Hospital, Hong Kong, China., Ng MY; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: myng2@hku.hk.
Source: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance [J Cardiovasc Magn Reson] 2026 Summer; Vol. 28 (1), pp. 102744. Date of Electronic Publication: 2026 May 12.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9815616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-429X (Electronic) Linking ISSN: 10976647 NLM ISO Abbreviation: J Cardiovasc Magn Reson Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Randomized controlled trial of vericiguat in patients with coronary microvascular dysfunction causing stable chest pain (V-COM): study protocol for a randomized control trial.
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  Data: <searchLink fieldCode="AU" term="%22Lo+CK%22">Lo CK</searchLink>; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Ip+NH%22">Ip NH</searchLink>; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Sin+TH%22">Sin TH</searchLink>; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Ho+SY%22">Ho SY</searchLink>; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wong+CK%22">Wong CK</searchLink>; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Tam+FC%22">Tam FC</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lam+SC%22">Lam SC</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Yiu+KH%22">Yiu KH</searchLink>; Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Sze+MS%22">Sze MS</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lam+TT%22">Lam TT</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Chiu+ACH%22">Chiu ACH</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Li+KK%22">Li KK</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Un+KC%22">Un KC</searchLink>; Department of Medicine, Queen Mary Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Yu+EY%22">Yu EY</searchLink>; Department of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Chan+EK%22">Chan EK</searchLink>; Department of Medicine, Grantham Hospital, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lee+KK%22">Lee KK</searchLink>; Department of Medicine and Geriatrics, Ruttonjee and Tang Shiu Kin Hospitals, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Ching+S%22">Ching S</searchLink>; Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lee+DP%22">Lee DP</searchLink>; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wong+CY%22">Wong CY</searchLink>; Department of Medicine, Queen Elizabeth Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+HL%22">Chan HL</searchLink>; Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+NY%22">Chan NY</searchLink>; Department of Medicine & Geriatrics, Princess Margaret Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Leung+CY%22">Leung CY</searchLink>; Department of Medicine, Tseung Kwan O Hospital, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Ng+MY%22">Ng MY</searchLink>; Department of Diagnostic Radiology, School of Clinical Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: myng2@hku.hk.
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  Data: <searchLink fieldCode="JN" term="%229815616%22">Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance</searchLink> [J Cardiovasc Magn Reson] 2026 Summer; Vol. 28 (1), pp. 102744. <i>Date of Electronic Publication: </i>2026 May 12.
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  Data: Journal Article; Randomized Controlled Trial
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9815616 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-429X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210976647%22">10976647 </searchLink><i>NLM ISO Abbreviation: </i>J Cardiovasc Magn Reson <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jocmr.2026.102744
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        Text: English
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      – TitleFull: Randomized controlled trial of vericiguat in patients with coronary microvascular dysfunction causing stable chest pain (V-COM): study protocol for a randomized control trial.
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              Text: 2026 Summer
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