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Metabolism and Excretion of Synthetic Extended Viperin Pathway Deoxydidehydronucleosides in the Sprague-Dawley Rat.

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Title: Metabolism and Excretion of Synthetic Extended Viperin Pathway Deoxydidehydronucleosides in the Sprague-Dawley Rat.
Authors: Sala S; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia., Nitschke P; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia., Castillo AM; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia., Bernal A; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia., Masuda R; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia., Wood JM; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand.; The Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand., Buckler JN; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand., Grove TL; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States., Almo SC; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States., Harris LD; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand.; The Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand., Holmes E; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States.; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, Burlington Danes Building, Du Cane Road, London W12 0NN, U.K., Wist J; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.; Chemistry Department, Universidad del Valle, Cali 76001, Colombia., Wilson ID; Institute of Global Health Innovation, Faculty of Medicine, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London SW7 2NA, U.K., Nicholson JK; Institute of Global Health Innovation, Faculty of Medicine, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London SW7 2NA, U.K.
Source: Journal of proteome research [J Proteome Res] 2026 Jun 05; Vol. 25 (6), pp. 2891-2900. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE
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  Data: Metabolism and Excretion of Synthetic Extended Viperin Pathway Deoxydidehydronucleosides in the Sprague-Dawley Rat.
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  Data: <searchLink fieldCode="AU" term="%22Sala+S%22">Sala S</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.<br /><searchLink fieldCode="AU" term="%22Nitschke+P%22">Nitschke P</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.<br /><searchLink fieldCode="AU" term="%22Castillo+AM%22">Castillo AM</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.<br /><searchLink fieldCode="AU" term="%22Bernal+A%22">Bernal A</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.<br /><searchLink fieldCode="AU" term="%22Masuda+R%22">Masuda R</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.<br /><searchLink fieldCode="AU" term="%22Wood+JM%22">Wood JM</searchLink>; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand.; The Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Buckler+JN%22">Buckler JN</searchLink>; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand.<br /><searchLink fieldCode="AU" term="%22Grove+TL%22">Grove TL</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States.<br /><searchLink fieldCode="AU" term="%22Almo+SC%22">Almo SC</searchLink>; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States.<br /><searchLink fieldCode="AU" term="%22Harris+LD%22">Harris LD</searchLink>; Victoria University of Wellington, Ferrier Research Institute, Wellington 6012, New Zealand.; The Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland 1010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Holmes+E%22">Holmes E</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, New York 10461, United States.; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, Burlington Danes Building, Du Cane Road, London W12 0NN, U.K.<br /><searchLink fieldCode="AU" term="%22Wist+J%22">Wist J</searchLink>; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth WA6150, Australia.; Chemistry Department, Universidad del Valle, Cali 76001, Colombia.<br /><searchLink fieldCode="AU" term="%22Wilson+ID%22">Wilson ID</searchLink>; Institute of Global Health Innovation, Faculty of Medicine, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London SW7 2NA, U.K.<br /><searchLink fieldCode="AU" term="%22Nicholson+JK%22">Nicholson JK</searchLink>; Institute of Global Health Innovation, Faculty of Medicine, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London SW7 2NA, U.K.
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        Value: 10.1021/acs.jproteome.5c01163
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              Text: 2026 Jun 05
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