Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD.
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| Title: | Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD. |
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| Authors: | Feng H; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China., Zheng J; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China., Li N; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Lab of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan, Hubei, China., Xie L; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China., Zuo E; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China. zuoerwei@caas.cn. |
| Source: | Cell discovery [Cell Discov] 2026 May 13; Vol. 12 (1). Date of Electronic Publication: 2026 May 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101661034 Publication Model: Electronic Cited Medium: Print ISSN: 2056-5968 (Print) Linking ISSN: 20565968 NLM ISO Abbreviation: Cell Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42129132 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Feng+H%22">Feng H</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Animal Science and Technology, Guangxi University, Nanning, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education & Key Lab of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zuo+E%22">Zuo E</searchLink>; State Key Laboratory of Genome and Multi-omics Technologies, Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Gene Editing Technologies (Hainan), Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Guangdong, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China. zuoerwei@caas.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101661034%22">Cell discovery</searchLink> [Cell Discov] 2026 May 13; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 May 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101661034 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2056-5968 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220565968%22">20565968 </searchLink><i>NLM ISO Abbreviation: </i>Cell Discov <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42129132 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41421-026-00889-2 Languages: – Code: eng Text: English Titles: – TitleFull: Decoding the role of chromatin context in the off-target effects of CRISPR gene editing with EGOLD. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Feng H – PersonEntity: Name: NameFull: Zheng J – PersonEntity: Name: NameFull: Li N – PersonEntity: Name: NameFull: Xie L – PersonEntity: Name: NameFull: Zuo E IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 05 Text: 2026 May 13 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2056-5968 Numbering: – Type: volume Value: 12 – Type: issue Value: 1 Titles: – TitleFull: Cell discovery Type: main |
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