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The role of sphingolipids in major depressive disorder and associated cognitive impairment: interactions with monoaminergic signaling, neuroinflammation, and neurogenesis.

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Title: The role of sphingolipids in major depressive disorder and associated cognitive impairment: interactions with monoaminergic signaling, neuroinflammation, and neurogenesis.
Authors: Hoertel N; AP-HP.Centre-Université Paris Cité, Département médico-universitaire (DMU) Psychiatrie et Addictologie, Hôpital Corentin-Celton, Issy-les-Moulineaux, France. nicolas.hoertel@aphp.fr.; Institut de Psychiatrie et Neurosciences de Paris, INSERM UMR_S1266, Paris, France. nicolas.hoertel@aphp.fr.; Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France. nicolas.hoertel@aphp.fr.; CERAMED, Paris, France. nicolas.hoertel@aphp.fr., Mühle C; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany., Müller CP; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany.; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Chaieb H; Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France.; CERAMED, Paris, France., Scheer V; AP-HP.Centre-Université Paris Cité, Département médico-universitaire (DMU) Psychiatrie et Addictologie, Hôpital Corentin-Celton, Issy-les-Moulineaux, France.; Institut de Psychiatrie et Neurosciences de Paris, INSERM UMR_S1266, Paris, France.; Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France., Fayad M; AP-HP.Centre-Université Paris Cité, Département médico-universitaire (DMU) Psychiatrie et Addictologie, Hôpital Corentin-Celton, Issy-les-Moulineaux, France.; Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France., Sánchez-Rico M; AP-HP.Centre-Université Paris Cité, Département médico-universitaire (DMU) Psychiatrie et Addictologie, Hôpital Corentin-Celton, Issy-les-Moulineaux, France.; CERAMED, Paris, France., Limosin F; AP-HP.Centre-Université Paris Cité, Département médico-universitaire (DMU) Psychiatrie et Addictologie, Hôpital Corentin-Celton, Issy-les-Moulineaux, France.; Institut de Psychiatrie et Neurosciences de Paris, INSERM UMR_S1266, Paris, France.; Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France., Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany.
Source: Molecular psychiatry [Mol Psychiatry] 2026 May 13. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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