A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability.
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| Title: | A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability. |
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| Authors: | Guha Majumdar A; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India.; Homi Bhabha National Institute, Mumbai, India., Chauhan N; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India.; Homi Bhabha National Institute, Mumbai, India., Gupta P; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India.; Homi Bhabha National Institute, Mumbai, India., Subramanian M; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India. maheshs@barc.gov.in.; Homi Bhabha National Institute, Mumbai, India. maheshs@barc.gov.in., Patro BS; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India. bisank@barc.gov.in.; Homi Bhabha National Institute, Mumbai, India. bisank@barc.gov.in. |
| Source: | The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (12), pp. 4220-4256. Date of Electronic Publication: 2026 May 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00783-3 |
