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One-step generation of T-cell receptor knock-in mice in the TCRβ locus.

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Title: One-step generation of T-cell receptor knock-in mice in the TCRβ locus.
Authors: Bilanovic J; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA., Bortolatto J; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA., Duan S; St. Jude Children's Research Hospital, Department of Immunology, Memphis, TN, USA., Bjørnsdottir V; University of Oslo, Department of Clinical Medicine, Oslo, Norway., Teetz AK; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Institute of Immunology, University of Muenster, Muenster, Germany., Thoms A; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA., Fischbach J; Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Schmidt F; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA.; Laboratory for Applied Virology and Precision Medicine, Division of Biological & Environmental Science & Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia., Nyberg WA; Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden., Hartweger H; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA., Escolano A; Laboratory of Immunobiology and Vaccines, Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, USA., Thomas PG; St. Jude Children's Research Hospital, Department of Immunology, Memphis, TN, USA., Victora GD; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA., Bilate AM; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. abilate@rockefeller.edu., Jacobsen JT; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. j.t.jacobsen@medisin.uio.no.; Department of Immunology, Oslo University Hospital, Oslo, Norway. j.t.jacobsen@medisin.uio.no.
Source: The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (12), pp. 4321-4336. Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bilanovic+J%22">Bilanovic J</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bortolatto+J%22">Bortolatto J</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Duan+S%22">Duan S</searchLink>; St. Jude Children's Research Hospital, Department of Immunology, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Bjørnsdottir+V%22">Bjørnsdottir V</searchLink>; University of Oslo, Department of Clinical Medicine, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Teetz+AK%22">Teetz AK</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Institute of Immunology, University of Muenster, Muenster, Germany.<br /><searchLink fieldCode="AU" term="%22Thoms+A%22">Thoms A</searchLink>; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fischbach+J%22">Fischbach J</searchLink>; Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Schmidt+F%22">Schmidt F</searchLink>; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA.; Laboratory for Applied Virology and Precision Medicine, Division of Biological & Environmental Science & Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nyberg+WA%22">Nyberg WA</searchLink>; Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hartweger+H%22">Hartweger H</searchLink>; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Escolano+A%22">Escolano A</searchLink>; Laboratory of Immunobiology and Vaccines, Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+PG%22">Thomas PG</searchLink>; St. Jude Children's Research Hospital, Department of Immunology, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Victora+GD%22">Victora GD</searchLink>; Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bilate+AM%22">Bilate AM</searchLink>; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. abilate@rockefeller.edu.<br /><searchLink fieldCode="AU" term="%22Jacobsen+JT%22">Jacobsen JT</searchLink>; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. j.t.jacobsen@medisin.uio.no.; Department of Immunology, Oslo University Hospital, Oslo, Norway. j.t.jacobsen@medisin.uio.no.
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