High folic acid supplementation is associated with vaginal bleeding in early pregnancy in a fetal sex-specific manner: findings from two prospective cohort studies.

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Title: High folic acid supplementation is associated with vaginal bleeding in early pregnancy in a fetal sex-specific manner: findings from two prospective cohort studies.
Authors: Wang H; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia. hongyan.wang@flinders.edu.au.; Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China. hongyan.wang@flinders.edu.au., Leemaqz S; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia., Smith MD; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia., McCullough D; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia., Arthurs AL; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia., Jankovic-Karasoulos T; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia., Dekker GA; Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; Department of Obstetrics and Gynaecology, Lyell McEwin Hospital, Elizabeth Vale, SA, Australia., Roberts CT; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia. claire.roberts@flinders.edu.au.
Source: Reproductive health [Reprod Health] 2026 May 13; Vol. 23 (1). Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101224380 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-4755 (Electronic) Linking ISSN: 17424755 NLM ISO Abbreviation: Reprod Health Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High folic acid supplementation is associated with vaginal bleeding in early pregnancy in a fetal sex-specific manner: findings from two prospective cohort studies.
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  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia. hongyan.wang@flinders.edu.au.; Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China. hongyan.wang@flinders.edu.au.<br /><searchLink fieldCode="AU" term="%22Leemaqz+S%22">Leemaqz S</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Smith+MD%22">Smith MD</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22McCullough+D%22">McCullough D</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Arthurs+AL%22">Arthurs AL</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Jankovic-Karasoulos+T%22">Jankovic-Karasoulos T</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Dekker+GA%22">Dekker GA</searchLink>; Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.; Department of Obstetrics and Gynaecology, Lyell McEwin Hospital, Elizabeth Vale, SA, Australia.<br /><searchLink fieldCode="AU" term="%22Roberts+CT%22">Roberts CT</searchLink>; College of Medicine and Public Health, and Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia. claire.roberts@flinders.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101224380%22">Reproductive health</searchLink> [Reprod Health] 2026 May 13; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 May 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101224380 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-4755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217424755%22">17424755 </searchLink><i>NLM ISO Abbreviation: </i>Reprod Health <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12978-026-02344-7
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      – TitleFull: High folic acid supplementation is associated with vaginal bleeding in early pregnancy in a fetal sex-specific manner: findings from two prospective cohort studies.
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              Text: 2026 May 13
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