Metabolic complications of citrate anticoagulation in continuous renal replacement therapy (crrt): a delphi consensus on indications, monitoring and management.

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Title: Metabolic complications of citrate anticoagulation in continuous renal replacement therapy (crrt): a delphi consensus on indications, monitoring and management.
Authors: Jacobs R; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium. rita.jacobs2@uza.be.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium. rita.jacobs2@uza.be., Schneider A; Adult Intensive Care Unit, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland., Hoste E; Intensive Care Unit, Dept of Internal Medicine and Paediatrics, Ghent University Hospital, Ghent University, C. Heymanslaan 10, Gent, Belgium., Verbrugghe W; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium., Bagshaw S; Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Canada., Bell M; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital, Stockholm, Sweden., Boer W; Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine & Pain Medicine, Ziekenhuis Oost Limburg ZOL, Genk, Belgium., Bouchard J; Professor of Medicine, FRCPC Nephrologist, University of Montreal, Montreal, Canada., Broman M; Överläkare Docent Perioperative and Intensive Care, Skåne University Hospital, Lund, Sweden., Crawford B; Division of Pediatric Nephrology, University of Arkansas Medical Sciences, Little Rock, AR, USA., David S; Institute of Intensive Care Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Di Mario F; Azienda Ospedaliero-Universitaria di Parma, Parma, Italy., Joannes-Boyau O; Service d'Anesthésie‑Réanimation Thoraco-abdominal, Centre Médico- Chirurgical Magellan, CHU de Bordeaux, Bordeaux, France., Joannidis M; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria., Joseph C; Division of Pediatric Nephrology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Merrill KA; University of Iowa Carver College of Medicine, Iowa City, IA, USA.; University of Iowa Healthcare Stead Family Children's Hospital, Iowa City, IA, USA., Ostermann M; Department of Intensive Care, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK., Palevsky P; Deputy National Program Executive Director, University of Pittsburgh School of MedicineVHA Kidney Medicine Program, Pittsburgh, USA., Papez K; Acute Care Nephrology, Phoenix Children's, Phoenix, AZ, USA., Prowle J; Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.; Critical Care and Peri-operative Medicine Research Group, William Harvey Research Institute, London, United Kingdom., Rewa O; Department of Critical Care Medicine, University of Alberta, Edmonton, Canada., Ricci Z; Department of Emergency and Critical Care, Anesthesia and Pediatric Intensive Care Unit, Meyer Children's Hospital, IRCCS, Florence, Italy.; Department of Health Science, Section of Anesthesia and Intensive Care, University of Florence, Florence, Italy., Shin S; Department of Pediatrics Atlanta, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, USA., Szamosfalvi B; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Tolwani A; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, USA., Villa G; Section of Anesthesiology, Intensive Care and Pain Medicine, Department of Health Sciences, Department of Anesthesia and Intensive Care, University of Florence, AOU Careggi, Florence, Italy., Volbeda M; Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Rimmelé T; Intensive Care Medicine, Hôpital Pasteur, Nice, France., Jorens PG; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium.
Source: Critical care (London, England) [Crit Care] 2026 May 13; Vol. 30 (1). Date of Electronic Publication: 2026 May 13.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolic complications of citrate anticoagulation in continuous renal replacement therapy (crrt): a delphi consensus on indications, monitoring and management.
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  Data: <searchLink fieldCode="AU" term="%22Jacobs+R%22">Jacobs R</searchLink>; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium. rita.jacobs2@uza.be.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium. rita.jacobs2@uza.be.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; Adult Intensive Care Unit, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hoste+E%22">Hoste E</searchLink>; Intensive Care Unit, Dept of Internal Medicine and Paediatrics, Ghent University Hospital, Ghent University, C. Heymanslaan 10, Gent, Belgium.<br /><searchLink fieldCode="AU" term="%22Verbrugghe+W%22">Verbrugghe W</searchLink>; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Bagshaw+S%22">Bagshaw S</searchLink>; Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta and Alberta Health Services, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Bell+M%22">Bell M</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Boer+W%22">Boer W</searchLink>; Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine & Pain Medicine, Ziekenhuis Oost Limburg ZOL, Genk, Belgium.<br /><searchLink fieldCode="AU" term="%22Bouchard+J%22">Bouchard J</searchLink>; Professor of Medicine, FRCPC Nephrologist, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Broman+M%22">Broman M</searchLink>; Överläkare Docent Perioperative and Intensive Care, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Crawford+B%22">Crawford B</searchLink>; Division of Pediatric Nephrology, University of Arkansas Medical Sciences, Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22David+S%22">David S</searchLink>; Institute of Intensive Care Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Di+Mario+F%22">Di Mario F</searchLink>; Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Joannes-Boyau+O%22">Joannes-Boyau O</searchLink>; Service d'Anesthésie‑Réanimation Thoraco-abdominal, Centre Médico- Chirurgical Magellan, CHU de Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Joannidis+M%22">Joannidis M</searchLink>; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Joseph+C%22">Joseph C</searchLink>; Division of Pediatric Nephrology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Merrill+KA%22">Merrill KA</searchLink>; University of Iowa Carver College of Medicine, Iowa City, IA, USA.; University of Iowa Healthcare Stead Family Children's Hospital, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Ostermann+M%22">Ostermann M</searchLink>; Department of Intensive Care, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.<br /><searchLink fieldCode="AU" term="%22Palevsky+P%22">Palevsky P</searchLink>; Deputy National Program Executive Director, University of Pittsburgh School of MedicineVHA Kidney Medicine Program, Pittsburgh, USA.<br /><searchLink fieldCode="AU" term="%22Papez+K%22">Papez K</searchLink>; Acute Care Nephrology, Phoenix Children's, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Prowle+J%22">Prowle J</searchLink>; Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.; Critical Care and Peri-operative Medicine Research Group, William Harvey Research Institute, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rewa+O%22">Rewa O</searchLink>; Department of Critical Care Medicine, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Ricci+Z%22">Ricci Z</searchLink>; Department of Emergency and Critical Care, Anesthesia and Pediatric Intensive Care Unit, Meyer Children's Hospital, IRCCS, Florence, Italy.; Department of Health Science, Section of Anesthesia and Intensive Care, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Shin+S%22">Shin S</searchLink>; Department of Pediatrics Atlanta, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Szamosfalvi+B%22">Szamosfalvi B</searchLink>; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Tolwani+A%22">Tolwani A</searchLink>; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, USA.<br /><searchLink fieldCode="AU" term="%22Villa+G%22">Villa G</searchLink>; Section of Anesthesiology, Intensive Care and Pain Medicine, Department of Health Sciences, Department of Anesthesia and Intensive Care, University of Florence, AOU Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Volbeda+M%22">Volbeda M</searchLink>; Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rimmelé+T%22">Rimmelé T</searchLink>; Intensive Care Medicine, Hôpital Pasteur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Jorens+PG%22">Jorens PG</searchLink>; Department of Critical Care Medicine, Antwerp University Hospital, UZA, Drie Eiken Straat 655, Edegem, B-2650, Belgium.; University of Antwerp, LEMP, Universiteitsplein 1, Antwerp, Belgium.
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