Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder.
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| Title: | Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder. |
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| Authors: | West RM; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Bizga Nicolescu RC; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Brear P; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, U.K., Wagstaff J; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, U.K., Blaszczyk BK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, U.K., Deingruber T; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Sanders MG; Oncology Targeted Discovery, Oncology R&D, The Discovery Centre, AstraZeneca, Cambridge CB2 0AA, U.K., Pérez-Areales FJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Spring DR; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K., Hyvönen M; Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, U.K. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2026 May 28; Vol. 69 (10), pp. 12099-12121. Date of Electronic Publication: 2026 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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