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Tumor necrosis factor-alpha-mediated inflammatory bone loss: Pathogenic mechanisms and therapeutic potential of its inhibitors.

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Title: Tumor necrosis factor-alpha-mediated inflammatory bone loss: Pathogenic mechanisms and therapeutic potential of its inhibitors.
Authors: Lin WY; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan., Pan YJ; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Division of Allergy, Immunology and Rheumatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Yeh KT; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Pharmacy, Tzu Chi University, Hualien, Taiwan., Su KY; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Division of Allergy, Immunology and Rheumatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Dharini KK; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan., Chen IH; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Wu WT; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Lin MD; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan.; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Center for Herbal Medicine and Natural Products Research, Tzu Chi University, Hualien, Taiwan., Peng CH; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Source: Tzu chi medical journal [Tzu Chi Med J] 2026 Apr 03; Vol. 38 (2), pp. 125-136. Date of Electronic Publication: 2026 Apr 03 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Wolters Kluwer-Medknow Country of Publication: India NLM ID: 101770275 Publication Model: eCollection Cited Medium: Internet ISSN: 2223-8956 (Electronic) Linking ISSN: 10163190 NLM ISO Abbreviation: Tzu Chi Med J Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor necrosis factor-alpha-mediated inflammatory bone loss: Pathogenic mechanisms and therapeutic potential of its inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Lin+WY%22">Lin WY</searchLink>; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pan+YJ%22">Pan YJ</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Division of Allergy, Immunology and Rheumatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+KT%22">Yeh KT</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Pharmacy, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+KY%22">Su KY</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Division of Allergy, Immunology and Rheumatology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Dharini+KK%22">Dharini KK</searchLink>; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IH%22">Chen IH</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+WT%22">Wu WT</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+MD%22">Lin MD</searchLink>; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan.; Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Center for Herbal Medicine and Natural Products Research, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+CH%22">Peng CH</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan.; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101770275%22">Tzu chi medical journal</searchLink> [Tzu Chi Med J] 2026 Apr 03; Vol. 38 (2), pp. 125-136. <i>Date of Electronic Publication: </i>2026 Apr 03 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer-Medknow%22">Wolters Kluwer-Medknow </searchLink><i>Country of Publication: </i>India <i>NLM ID: </i>101770275 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2223-8956 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210163190%22">10163190 </searchLink><i>NLM ISO Abbreviation: </i>Tzu Chi Med J <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.4103/tcmj.TCMJ-D-25-00128
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        Text: English
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            – D: 03
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              Text: 2026 Apr 03
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              Y: 2026
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