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The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in Nodularia sp. NIES-3585.

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Title: The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in Nodularia sp. NIES-3585.
Authors: D'Agostino PM; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany., de Castro RR; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.; Laboratory of Genomics and Biotechnology, Federal University of Pará, Av. Augusto Correa 1, 66075-110, Belem-PA, Brazil., Uka V; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.; Division of Pharmacy, Faculty of Medicine, University of Prishtina, st. Bulevardi i Dëshmorëve n.n., 10000 Prishtina, Republic of Kosovo., Saurav K; Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Novohradská 237, 379 01 Třeboň, Czech Republic., Kriukova Y; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany., Milzarek TM; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany., Sester A; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany., Schneider MP; Laboratory of Genomics and Biotechnology, Federal University of Pará, Av. Augusto Correa 1, 66075-110, Belem-PA, Brazil., Gulder TAM; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.
Source: ACS synthetic biology [ACS Synth Biol] 2026 Jun 19; Vol. 15 (6), pp. 2274-2283. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE
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  Data: The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in Nodularia sp. NIES-3585.
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  Data: <searchLink fieldCode="AU" term="%22D'Agostino+PM%22">D'Agostino PM</searchLink>; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22de+Castro+RR%22">de Castro RR</searchLink>; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.; Laboratory of Genomics and Biotechnology, Federal University of Pará, Av. Augusto Correa 1, 66075-110, Belem-PA, Brazil.<br /><searchLink fieldCode="AU" term="%22Uka+V%22">Uka V</searchLink>; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.; Division of Pharmacy, Faculty of Medicine, University of Prishtina, st. Bulevardi i Dëshmorëve n.n., 10000 Prishtina, Republic of Kosovo.<br /><searchLink fieldCode="AU" term="%22Saurav+K%22">Saurav K</searchLink>; Laboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Novohradská 237, 379 01 Třeboň, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kriukova+Y%22">Kriukova Y</searchLink>; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Milzarek+TM%22">Milzarek TM</searchLink>; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Sester+A%22">Sester A</searchLink>; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+MP%22">Schneider MP</searchLink>; Laboratory of Genomics and Biotechnology, Federal University of Pará, Av. Augusto Correa 1, 66075-110, Belem-PA, Brazil.<br /><searchLink fieldCode="AU" term="%22Gulder+TAM%22">Gulder TAM</searchLink>; Department of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.; Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101575075%22">ACS synthetic biology</searchLink> [ACS Synth Biol] 2026 Jun 19; Vol. 15 (6), pp. 2274-2283. <i>Date of Electronic Publication: </i>2026 May 14.
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              Text: 2026 Jun 19
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