Implantable living materials autonomously deliver therapeutics using contained engineered bacteria.

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Title: Implantable living materials autonomously deliver therapeutics using contained engineered bacteria.
Authors: Harimoto T; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Herrero Quevedo F; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Zillig J; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Schreiber S; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Wu Y; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Ahn CH; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., To T; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Thakur R; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA., Tatara AM; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Kang S; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Chen Z; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Lafuente-Gómez N; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Hanan B; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Pauer A; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Lightbown S; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA., Weitz DA; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Department of Physics, Harvard University, Cambridge, MA, USA., Mooney DJ; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.
Source: Science (New York, N.Y.) [Science] 2026 May 14; Vol. 392 (6799), pp. 729-734. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1095-9203
DOI:10.1126/science.aec2071