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Umbilical cord mesenchymal stromal cells for respiratory complications of COVID-19 infection (ProTrans): phase II randomized clinical trial.

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Title: Umbilical cord mesenchymal stromal cells for respiratory complications of COVID-19 infection (ProTrans): phase II randomized clinical trial.
Authors: Colmegna I; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; The Research Institute of the McGill University Health Centre (MUHC), McGill University, Montreal, Quebec, Canada; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada. Electronic address: ines.colmegna.med@ssss.gouv.qc.ca., Hudson M; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada., Biard L; INSERM U1342, Team ECSTRRA, Hôpital Saint Louis, Paris, France; AP-HP Hôpital Saint Louis, Service de Biostatistique et Information Médicale, Paris, France., Azuelos I; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Respiratory Division, Department of Medicine, McGill University, Montreal, Quebec, Canada., Davies L; NextCell Pharma AB, Huddinge, Sweden; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden., Hirsch A; Respiratory Division, Department of Medicine, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Center of Excellence in Thrombosis and Anticoagulation Care (CETAC), Jewish General Hospital, McGill University, Montreal, Quebec, Canada., Leger S; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada., McDonald EG; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Department of Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Clinical Practice Assessment Unit, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada; Centre for Outcomes Research and Evaluation, McGill University Health Centre, Montreal, Quebec, Canada., Peltier L; Cellular Therapy Laboratory, McGill University Health Centre (MUHC), McGill University, Montreal, Quebec, Canada., Popradi G; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Division of Hematology, Department of Medicine, McGill University, Montreal, Quebec, Canada., Resche-Rigon M; AP-HP, Department of Biostatistics and Medical Information, Saint-Louis Hospital, Paris, France; INSERM, UMR-1153, ECSTRRA Team, Paris, France., Robitaille C; Respiratory Division, Department of Medicine, Jewish General Hospital, McGill University, Montreal, Quebec, Canada., Svahn M; NextCell Pharma AB, Huddinge, Sweden., Walter-Petrich A; AP-HP Hôpital Saint Louis, Service de Biostatistique et Information Médicale, Paris, France., Martin JG; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Respiratory Division, Department of Medicine, McGill University, Montreal, Quebec, Canada., Farge-Bancel D; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; INSERM U1342, Team ECSTRRA, Hôpital Saint Louis, Paris, France; Internal Médicine Unit (04): CRMR MATHEC, Maladies Auto-immunes et Thérapie Cellulaire, Centre de Référence des Maladies auto-immunes systémiques Rares d'Ile-de-France, AP-HP, Hôpital Saint-Louis, Université Paris Cité, Paris, France.
Source: Cytotherapy [Cytotherapy] 2026 Jul; Vol. 28 (7), pp. 102775. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 100895309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2566 (Electronic) Linking ISSN: 14653249 NLM ISO Abbreviation: Cytotherapy Subsets: MEDLINE
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  Data: Umbilical cord mesenchymal stromal cells for respiratory complications of COVID-19 infection (ProTrans): phase II randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Colmegna+I%22">Colmegna I</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; The Research Institute of the McGill University Health Centre (MUHC), McGill University, Montreal, Quebec, Canada; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada. Electronic address: ines.colmegna.med@ssss.gouv.qc.ca.<br /><searchLink fieldCode="AU" term="%22Hudson+M%22">Hudson M</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Biard+L%22">Biard L</searchLink>; INSERM U1342, Team ECSTRRA, Hôpital Saint Louis, Paris, France; AP-HP Hôpital Saint Louis, Service de Biostatistique et Information Médicale, Paris, France.<br /><searchLink fieldCode="AU" term="%22Azuelos+I%22">Azuelos I</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Respiratory Division, Department of Medicine, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Davies+L%22">Davies L</searchLink>; NextCell Pharma AB, Huddinge, Sweden; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Hirsch+A%22">Hirsch A</searchLink>; Respiratory Division, Department of Medicine, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Center of Excellence in Thrombosis and Anticoagulation Care (CETAC), Jewish General Hospital, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Leger+S%22">Leger S</searchLink>; Division of Rheumatology, Department of Medicine, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22McDonald+EG%22">McDonald EG</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Department of Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Clinical Practice Assessment Unit, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada; Centre for Outcomes Research and Evaluation, McGill University Health Centre, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Peltier+L%22">Peltier L</searchLink>; Cellular Therapy Laboratory, McGill University Health Centre (MUHC), McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Popradi+G%22">Popradi G</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Division of Hematology, Department of Medicine, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Resche-Rigon+M%22">Resche-Rigon M</searchLink>; AP-HP, Department of Biostatistics and Medical Information, Saint-Louis Hospital, Paris, France; INSERM, UMR-1153, ECSTRRA Team, Paris, France.<br /><searchLink fieldCode="AU" term="%22Robitaille+C%22">Robitaille C</searchLink>; Respiratory Division, Department of Medicine, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Svahn+M%22">Svahn M</searchLink>; NextCell Pharma AB, Huddinge, Sweden.<br /><searchLink fieldCode="AU" term="%22Walter-Petrich+A%22">Walter-Petrich A</searchLink>; AP-HP Hôpital Saint Louis, Service de Biostatistique et Information Médicale, Paris, France.<br /><searchLink fieldCode="AU" term="%22Martin+JG%22">Martin JG</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Respiratory Division, Department of Medicine, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Farge-Bancel+D%22">Farge-Bancel D</searchLink>; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; INSERM U1342, Team ECSTRRA, Hôpital Saint Louis, Paris, France; Internal Médicine Unit (04): CRMR MATHEC, Maladies Auto-immunes et Thérapie Cellulaire, Centre de Référence des Maladies auto-immunes systémiques Rares d'Ile-de-France, AP-HP, Hôpital Saint-Louis, Université Paris Cité, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22100895309%22">Cytotherapy</searchLink> [Cytotherapy] 2026 Jul; Vol. 28 (7), pp. 102775. <i>Date of Electronic Publication: </i>2026 Mar 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100895309 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-2566 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214653249%22">14653249 </searchLink><i>NLM ISO Abbreviation: </i>Cytotherapy <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jcyt.2026.102775
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        Text: English
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              Text: 2026 Jul
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