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Pharmacologic activation of PHD2 sensitizes non-small cell lung cancer cells to osimertinib.

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Title: Pharmacologic activation of PHD2 sensitizes non-small cell lung cancer cells to osimertinib.
Authors: Kim JS; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea., Abeysiriwardhana HNI; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea., Kim DK; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea., Yoon TH; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea., Choi JH; Department of Biochemistry, School of Medicine, Jeju National University, Jeju 63243, Republic of Korea., Liang Z; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea., Kim JW; Jeju Institute of Korean Medicine, Jeju 63309, Republic of Korea., Liu KH; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea., Lim Y; Division of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea., Yu JS; College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea., Cho SK; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea; Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University, Jeju 63243, Republic of Korea. Electronic address: somikim@jejunu.ac.kr., Cho M; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea; Department of Biochemistry, School of Medicine, Jeju National University, Jeju 63243, Republic of Korea; ACHEMBIO Inc., Jeju 63169, Republic of Korea. Electronic address: moonjae.cho@jejunu.ac.kr.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119443. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacologic activation of PHD2 sensitizes non-small cell lung cancer cells to osimertinib.
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  Data: <searchLink fieldCode="AU" term="%22Kim+JS%22">Kim JS</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Abeysiriwardhana+HNI%22">Abeysiriwardhana HNI</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DK%22">Kim DK</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+TH%22">Yoon TH</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JH%22">Choi JH</searchLink>; Department of Biochemistry, School of Medicine, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Liang+Z%22">Liang Z</searchLink>; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JW%22">Kim JW</searchLink>; Jeju Institute of Korean Medicine, Jeju 63309, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Liu+KH%22">Liu KH</searchLink>; BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+Y%22">Lim Y</searchLink>; Division of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+JS%22">Yu JS</searchLink>; College of Pharmacy, Jeju National University, Jeju 63243, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+SK%22">Cho SK</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea; Faculty of Biotechnology, College of Applied Life Sciences, SARI, Jeju National University, Jeju 63243, Republic of Korea. Electronic address: somikim@jejunu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Cho+M%22">Cho M</searchLink>; Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju 63243, Republic of Korea; Department of Biochemistry, School of Medicine, Jeju National University, Jeju 63243, Republic of Korea; ACHEMBIO Inc., Jeju 63169, Republic of Korea. Electronic address: moonjae.cho@jejunu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119443. <i>Date of Electronic Publication: </i>2026 May 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.biopha.2026.119443
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              Text: 2026 Jul
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