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Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosis.

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Title: Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosis.
Authors: Naylor C; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Prosser G; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Bayliss T; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Berle LF; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Wallach JB; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Kim H; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Aguilera Olvera R; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Thompson S; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Ioerger TR; Department of Computer Science and Engineering, Texas A&M University, College Station, Texas 77843, United States., Simpson L; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Casanueva R; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., Guijarro-Lopez L; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760 Madrid, Spain., Read KD; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Wyatt PG; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Schnappinger D; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States., Barry CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Green SR; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Cleghorn LAT; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.
Source: ACS infectious diseases [ACS Infect Dis] 2026 Jun 12; Vol. 12 (6), pp. 2004-2014. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE
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