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1-deoxysphinganine promoted microglial glycolytic reprogramming and neuroinflammation in alzheimer's disease.

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Title: 1-deoxysphinganine promoted microglial glycolytic reprogramming and neuroinflammation in alzheimer's disease.
Authors: Ye T; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Lv X; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Fang Z; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Li Q; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Chen F; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Dong Y; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Xiang K; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Yang Y; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Dai C; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China., Do QL; Mind-Body Interface Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan.; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan., Sun J; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China. sunjwz@126.com., Su KP; Mind-Body Interface Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan. cobol@cmu.edu.tw.; College of Medicine, China Medical University, Taichung, Taiwan. cobol@cmu.edu.tw.; Office of Research and Development, Asia University, Taichung, Taiwan. cobol@cmu.edu.tw.; An-Nan Hospital, China Medical University, Tainan, Taiwan. cobol@cmu.edu.tw., Liu J; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China. wzjiaming_liu@163.com.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 14; Vol. 16 (1). Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 1-deoxysphinganine promoted microglial glycolytic reprogramming and neuroinflammation in alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Ye+T%22">Ye T</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lv+X%22">Lv X</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Fang+Z%22">Fang Z</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Dong+Y%22">Dong Y</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Xiang+K%22">Xiang K</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Dai+C%22">Dai C</searchLink>; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Do+QL%22">Do QL</searchLink>; Mind-Body Interface Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan.; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China. sunjwz@126.com.<br /><searchLink fieldCode="AU" term="%22Su+KP%22">Su KP</searchLink>; Mind-Body Interface Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan. cobol@cmu.edu.tw.; College of Medicine, China Medical University, Taichung, Taiwan. cobol@cmu.edu.tw.; Office of Research and Development, Asia University, Taichung, Taiwan. cobol@cmu.edu.tw.; An-Nan Hospital, China Medical University, Tainan, Taiwan. cobol@cmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; School of Public Health, Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China. wzjiaming_liu@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 May 14; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 May 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101562664 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2158-3188 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221583188%22">21583188 </searchLink><i>NLM ISO Abbreviation: </i>Transl Psychiatry <i>Subsets: </i>MEDLINE
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              Text: 2026 May 14
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