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SIRT6 overexpression counteracts chromatin aging in the male murine liver.

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Title: SIRT6 overexpression counteracts chromatin aging in the male murine liver.
Authors: Nagar R; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Schwartz Z; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Katz A; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Touitou N; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Sharon E; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel., Tzdaka K; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel., Waner O; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Shalev N; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Clo R; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Weiss L; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel., Epstein B; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel., Bernier M; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Shtark RB; Department of Oral Biology, Goldschleger School of Dental Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Banskota N; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Lam KG; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., De S; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Price NL; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Lerrer B; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel., Bar DZ; Department of Oral Biology, Goldschleger School of Dental Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., de Cabo R; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Cohen HY; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel. Haim.Cohen@biu.ac.il.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel. Haim.Cohen@biu.ac.il.
Source: Nature communications [Nat Commun] 2026 May 14; Vol. 17 (1). Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: SIRT6 overexpression counteracts chromatin aging in the male murine liver.
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  Data: <searchLink fieldCode="AU" term="%22Nagar+R%22">Nagar R</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Schwartz+Z%22">Schwartz Z</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Katz+A%22">Katz A</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Touitou+N%22">Touitou N</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Sharon+E%22">Sharon E</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Tzdaka+K%22">Tzdaka K</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Waner+O%22">Waner O</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Shalev+N%22">Shalev N</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Clo+R%22">Clo R</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Weiss+L%22">Weiss L</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Epstein+B%22">Epstein B</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Bernier+M%22">Bernier M</searchLink>; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shtark+RB%22">Shtark RB</searchLink>; Department of Oral Biology, Goldschleger School of Dental Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Banskota+N%22">Banskota N</searchLink>; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lam+KG%22">Lam KG</searchLink>; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22De+S%22">De S</searchLink>; Computational Biology and Genomics Core, Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Price+NL%22">Price NL</searchLink>; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lerrer+B%22">Lerrer B</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Bar+DZ%22">Bar DZ</searchLink>; Department of Oral Biology, Goldschleger School of Dental Medicine, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22de+Cabo+R%22">de Cabo R</searchLink>; Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+HY%22">Cohen HY</searchLink>; The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel. Haim.Cohen@biu.ac.il.; The Sagol Healthy Human Longevity Center, Bar-Ilan University, Ramat-Gan, Israel. Haim.Cohen@biu.ac.il.
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