In the absence of mitochondrial fusion unequal segregation of mitochondria drives mtDNA loss.

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Title: In the absence of mitochondrial fusion unequal segregation of mitochondria drives mtDNA loss.
Authors: Dengler L; Molecular Cell Biology, Institute of Cell Biology, University of Tübingen, Tübingen, Germany., Padovani F; Institute of Functional Epigenetics, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Munich, Germany., Lemke B; Quantitative Proteomics, Institute of Cell Biology, University of Tübingen, Tübingen, Germany., Brugger R; Cell Biology, University of Bayreuth, Bayreuth, Germany., Benedikt A; Institute of Functional Epigenetics, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Munich, Germany., Westermann B; Cell Biology, University of Bayreuth, Bayreuth, Germany., Maček B; Quantitative Proteomics, Institute of Cell Biology, University of Tübingen, Tübingen, Germany., Schmoller KM; Institute of Functional Epigenetics, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München, Munich, Germany., Ewald JC; Molecular Cell Biology, Institute of Cell Biology, University of Tübingen, Tübingen, Germany. jennifer-christina.ewald@uni-tuebingen.de.
Source: EMBO reports [EMBO Rep] 2026 Jun; Vol. 27 (12), pp. 3359-3393. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-026-00794-5