Bi-directional regulation between NAD/NAMPT and IFN-γ/PD-L1 axes via BRD4/IRF1 and mitochondrial respiration in metastatic cutaneous melanoma.
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| Title: | Bi-directional regulation between NAD/NAMPT and IFN-γ/PD-L1 axes via BRD4/IRF1 and mitochondrial respiration in metastatic cutaneous melanoma. |
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| Authors: | Fiorilla I; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Ghezzi B; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Ponzano A; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Moiso E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Riccardo F; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Tommasi N; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Avalle L; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Carrà G; San Luigi Gonzaga Hospital, Regione Gonzole, Orbassano, Italy.; Department of Clinical and Biological Sciences, University of Turin, Torino, Italy., Ugolini F; Histopathology and Molecular Diagnostics, Careggi University Hospital, Florence, Italy., Calussi E; Histopathology and Molecular Diagnostics, Careggi University Hospital, Florence, Italy., Todesco AM; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Digiovanni S; Department of Oncology, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Casone F; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Rizza G; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy., Ponzone L; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Szumera-Ciećkiewicz A; Biobank, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.; Department of Pathology and Laboratory Medicine, Maria Sklodowska- Curie National Research Institute of Oncology, Warsaw, Poland., Cavaletto M; Department of Sustainable Development and Ecological Transition, University of Eastern Piedmont, Vercelli, Italy., Porporato PE; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Conti L; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Riganti C; Department of Oncology, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Massi D; Department of Health Sciences, Section of Pathology, University of Florence, Florence, Italy.; Department of Molecular Pathobiology, New York University - College of Dentistry, New York, USA., Calautti E; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center 'Guido Tarone', University of Turin, Torino, Italy., Audrito V; Department of Science and Technological Innovation, University of Eastern Piedmont, Alessandria, Italy. valentina.audrito@uniupo.it.; Research Laboratories, Research and Innovation Department (DAIRI), Azienda Ospedaliera Universitaria AOU 'SS. Antonio e Biagio e Cesare Arrigo', Alessandria, Italy. valentina.audrito@uniupo.it. |
| Source: | Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2026 May 14; Vol. 45 (1). Date of Electronic Publication: 2026 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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