Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens.
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| Title: | Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens. |
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| Authors: | Demirsoy E; BC Cancer, Vancouver, BC, V5Z 1L3, Canada.; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada.; Genome Science and Technology Graduate Program, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada., Parkin TI; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Mihalynuk SE; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Dema AH; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Corrie L; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Heilker ME; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Kuecks-Winger HN; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Yanai A; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada.; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada., Birol UB; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada., McIlwee M; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., de Wet K; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., Knipscheer M; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., Bowes V; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., Tuytel V; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., Ritchie L; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada., Köster W; Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada., Berberov E; Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada., Cox WR; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada., Kotkoff M; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada., Thompson VC; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Warren RL; BC Cancer, Vancouver, BC, V5Z 1L3, Canada., Fraser E; Communicable Disease Prevention and Response, British Columbia Centre for Disease Control, Vancouver, BC, V6Z R4R, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada., Hoang LMN; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada., Hof F; Department of Chemistry, University of Victoria, Victoria, BC, V8P 5C2, Canada., Birol F; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada., Helbing CC; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada., Birol I; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada. inanc.birol@ubc.ca.; Genome Science and Technology Graduate Program, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada. inanc.birol@ubc.ca.; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada. inanc.birol@ubc.ca.; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada. inanc.birol@ubc.ca.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada. inanc.birol@ubc.ca. |
| Source: | Journal of animal science and biotechnology [J Anim Sci Biotechnol] 2026 May 15; Vol. 17 (1). Date of Electronic Publication: 2026 May 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101581293 Publication Model: Electronic Cited Medium: Print ISSN: 1674-9782 (Print) Linking ISSN: 16749782 NLM ISO Abbreviation: J Anim Sci Biotechnol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42135842 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Demirsoy+E%22">Demirsoy E</searchLink>; BC Cancer, Vancouver, BC, V5Z 1L3, Canada.; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada.; Genome Science and Technology Graduate Program, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.<br /><searchLink fieldCode="AU" term="%22Parkin+TI%22">Parkin TI</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Mihalynuk+SE%22">Mihalynuk SE</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Dema+AH%22">Dema AH</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Corrie+L%22">Corrie L</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Heilker+ME%22">Heilker ME</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Kuecks-Winger+HN%22">Kuecks-Winger HN</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Yanai+A%22">Yanai A</searchLink>; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada.; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada.<br /><searchLink fieldCode="AU" term="%22Birol+UB%22">Birol UB</searchLink>; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada.<br /><searchLink fieldCode="AU" term="%22McIlwee+M%22">McIlwee M</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22de+Wet+K%22">de Wet K</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22Knipscheer+M%22">Knipscheer M</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22Bowes+V%22">Bowes V</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22Tuytel+V%22">Tuytel V</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22Ritchie+L%22">Ritchie L</searchLink>; SJ Ritchie Research Farms, Abbotsford, BC, V4X 2N4, Canada.<br /><searchLink fieldCode="AU" term="%22Köster+W%22">Köster W</searchLink>; Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Berberov+E%22">Berberov E</searchLink>; Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK, S7N 5E3, Canada.<br /><searchLink fieldCode="AU" term="%22Cox+WR%22">Cox WR</searchLink>; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada.<br /><searchLink fieldCode="AU" term="%22Kotkoff+M%22">Kotkoff M</searchLink>; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada.<br /><searchLink fieldCode="AU" term="%22Thompson+VC%22">Thompson VC</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Warren+RL%22">Warren RL</searchLink>; BC Cancer, Vancouver, BC, V5Z 1L3, Canada.<br /><searchLink fieldCode="AU" term="%22Fraser+E%22">Fraser E</searchLink>; Communicable Disease Prevention and Response, British Columbia Centre for Disease Control, Vancouver, BC, V6Z R4R, Canada.; School of Population and Public Health, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22Hoang+LMN%22">Hoang LMN</searchLink>; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.<br /><searchLink fieldCode="AU" term="%22Hof+F%22">Hof F</searchLink>; Department of Chemistry, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Birol+F%22">Birol F</searchLink>; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada.<br /><searchLink fieldCode="AU" term="%22Helbing+CC%22">Helbing CC</searchLink>; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.<br /><searchLink fieldCode="AU" term="%22Birol+I%22">Birol I</searchLink>; British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC, V6Z R4R, Canada. inanc.birol@ubc.ca.; Genome Science and Technology Graduate Program, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada. inanc.birol@ubc.ca.; Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC, V5Z 4S6, Canada. inanc.birol@ubc.ca.; Amphoraxe Life Sciences Inc., Vancouver, BC, V6L 3C9, Canada. inanc.birol@ubc.ca.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada. inanc.birol@ubc.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101581293%22">Journal of animal science and biotechnology</searchLink> [J Anim Sci Biotechnol] 2026 May 15; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101581293 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1674-9782 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216749782%22">16749782 </searchLink><i>NLM ISO Abbreviation: </i>J Anim Sci Biotechnol <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42135842 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s40104-026-01417-8 Languages: – Code: eng Text: English Titles: – TitleFull: Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Demirsoy E – PersonEntity: Name: NameFull: Parkin TI – PersonEntity: Name: NameFull: Mihalynuk SE – PersonEntity: Name: NameFull: Dema AH – PersonEntity: Name: NameFull: Corrie L – PersonEntity: Name: NameFull: Heilker ME – PersonEntity: Name: NameFull: Kuecks-Winger HN – PersonEntity: Name: NameFull: Yanai A – PersonEntity: Name: NameFull: Birol UB – PersonEntity: Name: NameFull: McIlwee M – PersonEntity: Name: NameFull: de Wet K – PersonEntity: Name: NameFull: Knipscheer M – PersonEntity: Name: NameFull: Bowes V – PersonEntity: Name: NameFull: Tuytel V – PersonEntity: Name: NameFull: Ritchie L – PersonEntity: Name: NameFull: Köster W – PersonEntity: Name: NameFull: Berberov E – PersonEntity: Name: NameFull: Cox WR – PersonEntity: Name: NameFull: Kotkoff M – PersonEntity: Name: NameFull: Thompson VC – PersonEntity: Name: NameFull: Warren RL – PersonEntity: Name: NameFull: Fraser E – PersonEntity: Name: NameFull: Hoang LMN – PersonEntity: Name: NameFull: Hof F – PersonEntity: Name: NameFull: Birol F – PersonEntity: Name: NameFull: Helbing CC – PersonEntity: Name: NameFull: Birol I IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: 2026 May 15 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1674-9782 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Journal of animal science and biotechnology Type: main |
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