Periprostatic adipose tissue-derived adipokine profile in prostate cancer patients reveals two distinct molecular phenotypes linked to obesity-related comorbidities: multifaceted role of lipocalin-2.
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| Title: | Periprostatic adipose tissue-derived adipokine profile in prostate cancer patients reveals two distinct molecular phenotypes linked to obesity-related comorbidities: multifaceted role of lipocalin-2. |
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| Authors: | Pérez-Gómez JM; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Prats-Escribano A; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Gil-Duque I; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Arroyo-Millán L; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Huertas-Cabrera H; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Núñez-Santos MA; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., López-Ruiz DJ; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; Radiodiagnostics Service, HURS, Córdoba, 14004, Spain., Mata-Ordoñez F; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; Department of Pharmacy and Nutrition, Faculty of Biomedical and Health Sciences, European Madrid University, Madrid, 28670, Spain., González-Serrano T; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; Anatomical Pathology Service, HURS, Córdoba, 14004, Spain., Ortea I; Proteomics Unit, Centro de Investigación en Nanomateriales y Nanotecnología (CINN-CSIC), Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, 33011, Spain., Porcel-Pastrana F; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Álvarez-Benito M; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; Radiodiagnostics Service, HURS, Córdoba, 14004, Spain., Planque M; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Louvain, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Louvain, Belgium.; Spatial Metabolomics Expertise Center, VIB Center for Cancer Biology, VIB, Louvain, Belgium., Carrasco-Valiente J; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; Urology Service, HURS, Córdoba, 14004, Spain., Gómez-Gómez E; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Guzmán-Ruiz R; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Fuentes-Fayos AC; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Louvain, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Louvain, Belgium., Gahete MD; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Sarmento-Cabral A; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain., Malagón MDM; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Luque RM; Department of Cell Biology, Physiology, and Immunology, University of Cordoba, Cordoba, 14004, Spain. raul.luque@uco.es.; Maimonides Biomedical Research Institute of Cordoba, IMIBIC Building. Av. Menéndez Pidal S/N., Córdoba, 14004, Spain. raul.luque@uco.es.; Reina Sofia University Hospital (HURS), Córdoba, 14004, Spain. raul.luque@uco.es.; CIBER Physiopathology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain. raul.luque@uco.es. |
| Source: | Cell communication and signaling : CCS [Cell Commun Signal] 2026 May 14; Vol. 24 (1). Date of Electronic Publication: 2026 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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