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Extended Barrier Precautions vs Hand Hygiene Alone and Neonatal Sepsis in Intensive Care Patients: The BALTIC Cluster-Randomized Clinical Trial.

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Title: Extended Barrier Precautions vs Hand Hygiene Alone and Neonatal Sepsis in Intensive Care Patients: The BALTIC Cluster-Randomized Clinical Trial.
Authors: Faust K; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany., Strecker F; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany., Haug C; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany., Felderhoff-Müser U; Department of Pediatrics I, University of Duisburg-Essen, Essen, Germany., Stein A; Department of Pediatrics I, University of Duisburg-Essen, Essen, Germany., Jensen R; Children's Hospital Westküstenklinikum, Heide, Germany., Fortmann MI; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany., Marißen J; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany., Silwedel C; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany., Brebach K; Children's Hospital Memmingen, Memmingen, Germany., Frommhold D; Children's Hospital Memmingen, Memmingen, Germany., Wieg C; Children's Hospital Aschaffenburg-Alzenau, Aschaffenburg, Germany., Hillebrand G; Children's Hospital Itzehoe, Itzehoe, Germany., Naust B; Children's Hospital Itzehoe, Itzehoe, Germany., Schmidt E; Helios Children's Hospital Schwerin, Schwerin, Germany., Koch L; Children's Hospital Wilhelmstift Hamburg, Marienhospital Hamburg, Hamburg, Germany., Schmidtke S; Neonatology, Asklepios Hospital Hamburg-Barmbek, Hamburg, Germany., Simon A; Department of Pediatric Hematology and Immunology, Saarland University Medical Center, Homburg, Germany., Zemlin M; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany., Meyer S; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany.; SKK Klinikum, Franz-Lust Children's Hospital, Karlsruhe, Germany., Scholzen C; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany., Köstlin-Gille N; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany.; Department of Neonatology, University Hospital Heidelberg, Heidelberg, Germany., Gille C; Department of Neonatology, University Hospital Heidelberg, Heidelberg, Germany., Longardt AC; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany., Göpel W; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany., Krone M; Infection Control and Antimicrobial Stewardship Unit, University Hospital Würzburg, Würzburg, Germany.; Central Laboratory Unit, University Hospital Würzburg, Würzburg, Germany., Kampmeier S; Infection Control and Antimicrobial Stewardship Unit, University Hospital Würzburg, Würzburg, Germany., Nurjadi D; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Institute of Medical Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany., Herting E; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany., Rupp J; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Institute of Medical Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.; Infectious Disease Clinic, University Hospital Schleswig-Holstein, Campus Lübeck, Germany., König IR; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany., Härtel C; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.
Source: JAMA network open [JAMA Netw Open] 2026 May 01; Vol. 9 (5), pp. e2612759. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Equivalence Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Extended Barrier Precautions vs Hand Hygiene Alone and Neonatal Sepsis in Intensive Care Patients: The BALTIC Cluster-Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Faust+K%22">Faust K</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Strecker+F%22">Strecker F</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Haug+C%22">Haug C</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Felderhoff-Müser+U%22">Felderhoff-Müser U</searchLink>; Department of Pediatrics I, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Stein+A%22">Stein A</searchLink>; Department of Pediatrics I, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Jensen+R%22">Jensen R</searchLink>; Children's Hospital Westküstenklinikum, Heide, Germany.<br /><searchLink fieldCode="AU" term="%22Fortmann+MI%22">Fortmann MI</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Marißen+J%22">Marißen J</searchLink>; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Silwedel+C%22">Silwedel C</searchLink>; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Brebach+K%22">Brebach K</searchLink>; Children's Hospital Memmingen, Memmingen, Germany.<br /><searchLink fieldCode="AU" term="%22Frommhold+D%22">Frommhold D</searchLink>; Children's Hospital Memmingen, Memmingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wieg+C%22">Wieg C</searchLink>; Children's Hospital Aschaffenburg-Alzenau, Aschaffenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hillebrand+G%22">Hillebrand G</searchLink>; Children's Hospital Itzehoe, Itzehoe, Germany.<br /><searchLink fieldCode="AU" term="%22Naust+B%22">Naust B</searchLink>; Children's Hospital Itzehoe, Itzehoe, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+E%22">Schmidt E</searchLink>; Helios Children's Hospital Schwerin, Schwerin, Germany.<br /><searchLink fieldCode="AU" term="%22Koch+L%22">Koch L</searchLink>; Children's Hospital Wilhelmstift Hamburg, Marienhospital Hamburg, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidtke+S%22">Schmidtke S</searchLink>; Neonatology, Asklepios Hospital Hamburg-Barmbek, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+A%22">Simon A</searchLink>; Department of Pediatric Hematology and Immunology, Saarland University Medical Center, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zemlin+M%22">Zemlin M</searchLink>; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+S%22">Meyer S</searchLink>; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany.; SKK Klinikum, Franz-Lust Children's Hospital, Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Scholzen+C%22">Scholzen C</searchLink>; Department for General Pediatrics and Neonatology, Saarland University Medical Center, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Köstlin-Gille+N%22">Köstlin-Gille N</searchLink>; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany.; Department of Neonatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gille+C%22">Gille C</searchLink>; Department of Neonatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Longardt+AC%22">Longardt AC</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Göpel+W%22">Göpel W</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Krone+M%22">Krone M</searchLink>; Infection Control and Antimicrobial Stewardship Unit, University Hospital Würzburg, Würzburg, Germany.; Central Laboratory Unit, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kampmeier+S%22">Kampmeier S</searchLink>; Infection Control and Antimicrobial Stewardship Unit, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nurjadi+D%22">Nurjadi D</searchLink>; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Institute of Medical Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Herting+E%22">Herting E</searchLink>; Department of Pediatrics, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Rupp+J%22">Rupp J</searchLink>; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Institute of Medical Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.; Infectious Disease Clinic, University Hospital Schleswig-Holstein, Campus Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22König+IR%22">König IR</searchLink>; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Härtel+C%22">Härtel C</searchLink>; German Center for Infection Research, Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2026 May 01; Vol. 9 (5), pp. e2612759. <i>Date of Electronic Publication: </i>2026 May 01.
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