Atomistic scattering modeling of the solution structure of human dimeric IgA1 reveals a structural and mechanistic basis for IgA nephropathy.

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Title: Atomistic scattering modeling of the solution structure of human dimeric IgA1 reveals a structural and mechanistic basis for IgA nephropathy.
Authors: Bhatt JS; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom., Yeo SC; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom., Ireland SM; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom., Ben-Younis A; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom., Gor J; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom., Molyneux K; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom., Barratt J; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom., Perkins SJ; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom. Electronic address: s.perkins@ucl.ac.uk.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Jul; Vol. 302 (7), pp. 113156. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Atomistic scattering modeling of the solution structure of human dimeric IgA1 reveals a structural and mechanistic basis for IgA nephropathy.
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  Data: <searchLink fieldCode="AU" term="%22Bhatt+JS%22">Bhatt JS</searchLink>; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Yeo+SC%22">Yeo SC</searchLink>; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ireland+SM%22">Ireland SM</searchLink>; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ben-Younis+A%22">Ben-Younis A</searchLink>; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gor+J%22">Gor J</searchLink>; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Molyneux+K%22">Molyneux K</searchLink>; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Barratt+J%22">Barratt J</searchLink>; Department of Cardiovascular Medicine, University of Leicester, Leicester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Perkins+SJ%22">Perkins SJ</searchLink>; Division of Biosciences, Department of Structural and Molecular Biology, University College London, London, United Kingdom. Electronic address: s.perkins@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2026 Jul; Vol. 302 (7), pp. 113156. <i>Date of Electronic Publication: </i>2026 May 14.
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        Value: 10.1016/j.jbc.2026.113156
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        Text: English
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              Text: 2026 Jul
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              Y: 2026
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